Vigilancia del Proceso de Implementación en Enfermedad Renal Crónica

9.8. Vigilancia del proceso de implementación

El proceso de vigilancia de la implementación de la guía se presenta en la figura 19. Para supervisar el proceso de implementación, se diseñaron indicadores, según las recomendaciones establecidas.

Proceso de vigilancia del paciente con enfermedad renal crónica

Los indicadores propuestos están fundamentados en dos metodologías:

1. Metodología del Balanced Score Card, agrupados en dos categorías:

  • Indicadores de gestión: describen el proceso de implementación de la GPC.
  • Indicadores de resultado clínico: describen las consecuencias en salud de la implementación de las recomendaciones. Corresponden a aspectos clínicos y asistenciales específicos que los expertos han considerado adecuados para el seguimiento de las recomendaciones propuestas en la GPC.

2. Clasificación de indicadores según la teoría de servicios de salud propuesta por Donabedian, et al.(624, 625), la cual clasifica los indicadores en tres categorías:

a) indicadores de estructura,
b) indicadores de proceso, e
c) indicadores de resultado.

Referencias

  • 1. Ministerio de Salud y de la Protección Social, Fundación Santafé de Bogotá. Guía Metodológica para la elaboración de Guías de Práctica Clínica con Evaluación Económica en el Sistema General de Seguridad Social en Salud Colombiano. Bogotá: 2014.
  • 2. Kidney Disease: Improving Global Outcomes CKD Work Group. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney international Supplement. 2013;3(1):1-150.
  • 3. Stanifer JW, Muiru A, Jafar TH, Patel UD. Chronic kidney disease in low- and middleincome countries. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2016;31(6):868-74.
  • 4. Mills KT, Xu Y, Zhang W, Bundy JD, Chen CS, Kelly TN, et al. A systematic analysis of worldwide population-based data on the global burden of chronic kidney disease in 2010. Kidney international. 2015;88(5):950-7.
  • 5. Jha V, Garcia-Garcia G, Iseki K, Li Z, Naicker S, Plattner B, et al. Chronic kidney disease: global dimension and perspectives. Lancet. 2013;382(9888):260-72.
  • 6. Mortality GBD, Causes of Death C. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;385(9963):117-71.
  • 7. Cuenta de Alto Costo. Situación de la enfermedad renal crónica, hipertensión arterial y diabetes mellitus en Bogotá. Bogotá: Cuenta de Alto Costo; 2015.
  • 8. Ministerio de la Protección Social. Guía para el manejo de la enfermedad renal crónica -ERC- basada en la evidencia. Bogotá, Colombia2005. 157 p.
  • 9. Brouwers M, Kho M, Browman G, Burgers J, Cluzeau F, Feder G, et al. AGREE II: Advancing guideline development, reporting and evaluation in healthcare. Can Med Assoc J. 2010;182:839-42.
  • 10. National Clinical Guideline Centre. Chronic kidney disease (partial update). Early identification and management of chronic kidney disease in adults in primary and secondary care. Clinical Guideline 182. Methods, evidence and recommendations. London: National Institute for Health and Clincal Excellence (NICE); 2014.
  • 11. Andrews J, Guyatt G, Oxman AD, Alderson P, Dahm P, Falck-Ytter Y, et al. GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations. Journal of Clinical Epidemiology. 2013;66(7):719-25.
  • 12. Andrews JC, Schünemann HJ, Oxman AD, Pottie K, Meerpohl JJ, Coello PA, et al. GRADE guidelines: 15. Going from evidence to recommendation—determinants of a recommendation’s direction and strength. Journal of Clinical Epidemiology. 2013;66(7):726- 35.
  • 13. Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC medical research methodology. 2007;7:10.
  • 14. Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. Bmj. 2011;343:d5928.
  • 15. Matsushita K Fau – van der Velde M, van der Velde M Fau – Astor BC, Astor Bc Fau – Woodward M, Woodward M Fau – Levey AS, Levey As Fau – de Jong PE, de Jong Pe Fau – Coresh J, et al. Association of estimated glomerular filtration rate and albuminuria with allcause and cardiovascular mortality in general population cohorts: a collaborative metaanalysis. Lancet. 2010;375(1474-547X (Electronic)):2073-81.
  • 16. Levey AS, de Jong PE, Coresh J, El Nahas M, Astor BC, Matsushita K, et al. The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report. Kidney international. 2011;80(1):17-28.
  • 17. Hsu CY, Ordonez JD, Chertow GM, Fan D, McCulloch CE, Go AS. The risk of acute renal failure in patients with chronic kidney disease. Kidney international. 2008;74(1):101-7.
  • 18. Hailpern SM, Melamed ML, Cohen HW, Hostetter TH. Moderate chronic kidney disease and cognitive function in adults 20 to 59 years of age: Third National Health and Nutrition Examination Survey (NHANES III). J Am Soc Nephrol. 2007;18(7):2205-13.
  • 19. James MT, Hemmelgarn BR, Wiebe N, Pannu N, Manns BJ, Klarenbach SW, et al. Glomerular filtration rate, proteinuria, and the incidence and consequences of acute kidney injury: a cohort study. Lancet. 2010;376(9758):2096-103.
  • 20. James MT, Quan H, Tonelli M, Manns BJ, Faris P, Laupland KB, et al. CKD and risk of hospitalization and death with pneumonia. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2009;54(1):24-32.
  • 21. Wilhelm-Leen ER, Hall YN, M KT, Chertow GM. Frailty and chronic kidney disease: the Third National Health and Nutrition Evaluation Survey. The American journal of medicine. 2009;122(7):664-71 e2.
  • 22. Levey AS, Coresh J. Chronic kidney disease. Lancet. 2012;379(9811):165-80.
  • 23. Group. KAW. KDIGO clinical practice guideline for acute kidney injury. Kidney inter. 2012;2:1-138.
  • 24. Wesson LG. Physiology of the human kidney. New York: Grune & Stratton; 1969.
  • 25. Rowe JW, Andres R, Tobin JD. Letter: Age-adjusted standards for creatinine clearance. Annals of internal medicine. 1976;84(5):567-9.
  • 26. Poggio ED, Rule AD, Tanchanco R, Arrigain S, Butler RS, Srinivas T, et al. Demographic and clinical characteristics associated with glomerular filtration rates in living kidney donors. Kidney international. 2009;75(10):1079-87.
  • 27. Rule AD, Amer H, Cornell LD, Taler SJ, Cosio FG, Kremers WK, et al. The association between age and nephrosclerosis on renal biopsy among healthy adults. Annals of internal medicine. 2010;152(9):561-7.
  • 28. Barai S, Gambhir S, Prasad N, Sharma RK, Ora M, Kumar A, et al. Levels of GFR and protein-induced hyperfiltration in kidney donors: a single-center experience in India. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2008;51(3):407-14.
  • 29. Eastwood JB, Kerry SM, Plange-Rhule J, Micah FB, Antwi S, Boa FG, et al. Assessment of GFR by four methods in adults in Ashanti, Ghana: the need for an eGFR equation for lean African populations. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2010;25(7):2178-87.
  • 30. Jafar TH, Islam M, Jessani S, Bux R, Inker LA, Mariat C, et al. Level and determinants of kidney function in a South Asian population in Pakistan. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2011;58(5):764- 72.
  • 31. Stevens LA, Coresh J Fau – Greene T, Greene T Fau – Levey AS, Levey AS. Assessing kidney function-measured and estimated glomerular filtration rate. The New England journal of medicine. 2006;354(1533-4406 (Electronic)):2473-83.
  • 32. Matzke GR, Aronoff Gr Fau – Atkinson AJ, Jr., Atkinson Aj Jr Fau – Bennett WM, Bennett Wm Fau – Decker BS, Decker Bs Fau – Eckardt K-U, Eckardt Ku Fau – Golper T, et al. Drug dosing consideration in patients with acute and chronic kidney disease-a clinical update from Kidney Disease: Improving Global Outcomes (KDIGO). (1523-1755 (Electronic)).
  • 33. Gansevoort RT, Matsushita K Fau – van der Velde M, van der Velde M Fau – Astor BC, Astor Bc Fau – Woodward M, Woodward M Fau – Levey AS, Levey As Fau – de Jong PE, et al. Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts. Kidney international. 2011;80(1523-1755 (Electronic)):93-104.
  • 34. Van der Velde M, Matsushita K Fau – Coresh J, Coresh J Fau – Astor BC, Astor Bc Fau – Woodward M, Woodward M Fau – Levey A, Levey A Fau – de Jong P, et al. Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts. Kidney international. 2011;79(1523-1755 (Electronic)):1341-52.
  • 35. Remuzzi G, Benigni A, Remuzzi A. Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes. The Journal of clinical investigation. 2006;116(2):288-96.
  • 36. KDIGO Transplant Work Group. KDIGO clinical practice guideline for the care of kidney transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2009;9:1-155.
  • 37. Levey AS, Eckardt KU, Tsukamoto Y, Levin A, Coresh J, Rossert J, et al. Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney international. 2005;67(6):2089-100.
  • 38. Eckardt KU, Berns JS, Rocco MV, Kasiske BL. Definition and classification of CKD: the debate should be about patient prognosis–a position statement from KDOQI and KDIGO. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2009;53(6):915-20.
  • 39. Winearls CG, Glassock RJ. Dissecting and refining the staging of chronic kidney disease. Kidney international. 2009;75(10):1009-14.
  • 40. Eknoyan G. Chronic kidney disease definition and classification: no need for a rush to judgment. Kidney international. 2009;75(10):1015-8.
  • 41. El Nahas M. Cardio-Kidney-Damage: a unifying concept. Kidney international. 2010;78(1):14-8.
  • 42. Levey AS, Astor BC, Stevens LA, Coresh J. Chronic kidney disease, diabetes, and hypertension: what’s in a name? Kidney international. 2010;78(1):19-22.
  • 43. Silva FG. The aging kidney: a review — part I. International urology and nephrology. 2005;37(1):185-205.
  • 44. Silva FG. The aging kidney: a review–part II. International urology and nephrology. 2005;37(2):419-32.
  • 45. Weinstein JR, Anderson S. The aging kidney: physiological changes. Advances in chronic kidney disease. 2010;17(4):302-7.
  • 46. King AJ, Levey AS. Dietary protein and renal function. J Am Soc Nephrol. 1993;3(11):1723-37.
  • 47. Seliger SL, Zhan M, Hsu VD, Walker LD, Fink JC. Chronic kidney disease adversely influences patient safety. J Am Soc Nephrol. 2008;19(12):2414-9.
  • 48. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. The New England journal of medicine. 2004;351(13):1296-305.
  • 49. Coresh J, Astor BC, Greene T. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2003;41:1-12.
  • 50. Earley A, Miskulin D, Lamb EJ, Levey AS, Uhlig K. Estimating equations for glomerular filtration rate in the era of creatinine standardization: a systematic review. Annals of internal medicine. 2012;156(11):785-95.
  • 51. Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Annals of internal medicine. 2006;145(4):247-54.
  • 52. Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF, 3rd, Feldman HI, et al. A new equation to estimate glomerular filtration rate. Annals of internal medicine. 2009;150(9):604-12.
  • 53. Horio M, Imai E, Yasuda Y, Watanabe T, Matsuo S. Modification of the CKD epidemiology collaboration (CKD-EPI) equation for Japanese: accuracy and use for population estimates. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2010;56(1):32-8.
  • 54. Imai E, Horio M Fau – Nitta K, Nitta K Fau – Yamagata K, Yamagata K Fau – Iseki K, Iseki K Fau – Hara S, Hara S Fau – Ura N, et al. Estimation of glomerular filtration rate by the MDRD study equation modified for Japanese patients with chronic kidney disease. Clinical and experimental nephrology. 2007;11(4):41-50.
  • 55. Praditpornsilpa K, Townamchai N, Chaiwatanarat T, Tiranathanagul K, Katawatin P, Susantitaphong P, et al. The need for robust validation for MDRD-based glomerular filtration rate estimation in various CKD populations. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2011;26(9):2780-5.
  • 56. Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, et al. Revised equations for estimated GFR from serum creatinine in Japan. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2009;53(6):982-92.
  • 57. Levey A, Greene T, Kusek J. A simplified equation to predict glomerular filtration rate from serum creatinine. J Am Soc Nephrol 2000;11:155A.
  • 58. Ma YC, Zuo L, Chen JH, Luo Q, Yu XQ, Li Y, et al. Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease. J Am Soc Nephrol. 2006;17(10):2937-44.
  • 59. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Annals of internal medicine. 1999;130(6):461-70.
  • 60. Kilpatrick ES, Verrill H. A national audit of estimated glomerular filtration rate and proteinuria reporting in the UK. Annals of clinical biochemistry. 2011;48(Pt 6):558-61.
  • 61. Murata K, Baumann Na Fau – Saenger AK, Saenger Ak Fau – Larson TS, Larson Ts Fau – Rule AD, Rule Ad Fau – Lieske JC, Lieske JC. Relative performance of the MDRD and CKD-EPI equations for estimating glomerular filtration rate among patients with varied clinical presentations. Clinical journal of the American Society of Nephrology : CJASN. 2011;6(1555-905X (Electronic)):1963-72.
  • 62. Lane BR, Demirjian S, Weight CJ, Larson BT, Poggio ED, Campbell SC. Performance of the chronic kidney disease-epidemiology study equations for estimating glomerular filtration rate before and after nephrectomy. The Journal of urology. 2010;183(3):896-901.
  • 63. Michels WM, Grootendorst DC, Verduijn M, Elliott EG, Dekker FW, Krediet RT. Performance of the Cockcroft-Gault, MDRD, and new CKD-EPI formulas in relation to GFR, age, and body size. Clinical journal of the American Society of Nephrology : CJASN. 2010;5(6):1003-9.
  • 64. Tent H, Rook M, Stevens LA, van Son WJ, van Pelt LJ, Hofker HS, et al. Renal function equations before and after living kidney donation: a within-individual comparison of performance at different levels of renal function. Clinical journal of the American Society of Nephrology : CJASN. 2010;5(11):1960-8.
  • 65. Kukla A, El-Shahawi Y, Leister E, Kasiske B, Mauer M, Matas A, et al. GFRestimating models in kidney transplant recipients on a steroid-free regimen. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2010;25(5):1653-61.
  • 66. White CA, Akbari A, Doucette S, Fergusson D, Knoll GA. Estimating glomerular filtration rate in kidney transplantation: is the new chronic kidney disease epidemiology collaboration equation any better? Clinical chemistry. 2010;56(3):474-7.
  • 67. Poge U, Gerhardt T, Stoffel-Wagner B, Sauerbruch T, Woitas RP. Validation of the CKD-EPI formula in patients after renal transplantation. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2011;26(12):4104-8.
  • 68. Jones GR, Imam SK. Validation of the revised MDRD formula and the original Cockcroft and Gault formula for estimation of the glomerular filtration rate using Australian data. Pathology. 2009;41(4):379-82.
  • 69. Jones GR. Use of the CKD-EPI equation for estimation of GFR in an Australian cohort. Pathology. 2010;42(5):487-8.
  • 70. Cirillo M, Lombardi C, Luciano MG, Bilancio G, Anastasio P, De Santo NG. Estimation of GFR: a comparison of new and established equations. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2010;56(4):802-4.
  • 71. Eriksen BO, Mathisen UD, Melsom T, Ingebretsen OC, Jenssen TG, Njolstad I, et al. Cystatin C is not a better estimator of GFR than plasma creatinine in the general population. Kidney international. 2010;78(12):1305-11.
  • 72. Redal-Baigorri B, Stokholm KH, Rasmussen K, Jeppesen N. Estimation of kidney function in cancer patients. Danish medical bulletin. 2011;58(2):A4236.
  • 73. Matsushita K, Mahmoodi BK, Woodward M, Emberson JR, Jafar TH, Jee SH, et al. Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate. JAMA. 2012;307(18):1941-51.
  • 74. Stevens LA, Claybon MA, Schmid CH, Chen J, Horio M, Imai E, et al. Evaluation of the Chronic Kidney Disease Epidemiology Collaboration equation for estimating the glomerular filtration rate in multiple ethnicities. Kidney international. 2011;79(5):555-62.
  • 75. Yeo Y, Han DJ, Moon DH, Park JS, Yang WS, Chang JW, et al. Suitability of the IDMS-traceable MDRD equation method to estimate GFR in early postoperative renal transplant recipients. Nephron Clinical practice. 2010;114(2):c108-17.
  • 76. van Deventer HE, George JA, Paiker JE, Becker PJ, Katz IJ. Estimating glomerular filtration rate in black South Africans by use of the modification of diet in renal disease and Cockcroft-Gault equations. Clinical chemistry. 2008;54(7):1197-202.
  • 77. Teo BW, Xu H, Wang D, Li J, Sinha AK, Shuter B, et al. GFR estimating equations in a multiethnic Asian population. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2011;58(1):56-63
  • 78. Stevens LA, Levey AS. Measured GFR as a confirmatory test for estimated GFR. J Am Soc Nephrol. 2009;20(11):2305-13.
  • 79. Stevens LA, Coresh J, Greene T, Levey AS. Assessing kidney function–measured and estimated glomerular filtration rate. The New England journal of medicine. 2006;354(23):2473-83.
  • 80. Newman DJ, Thakkar H, Medcalf EA, Gray MR, Price CP. Use of urine albumin measurement as a replacement for total protein. Clinical nephrology. 1995;43(2):104-9.
  • 81. Vieux R, Hascoet JM, Merdariu D, Fresson J, Guillemin F. Glomerular filtration rate reference values in very preterm infants. Pediatrics. 2010;125(5):e1186-92.
  • 82. Myers GL, Miller WG, Coresh J, Fleming J, Greenberg N, Greene T, et al. Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program. Clinical chemistry. 2006;52(1):5-18.
  • 83. Miller WG. Estimating glomerular filtration rate. Clinical chemistry and laboratory medicine. 2009;47(9):1017-9.
  • 84. McIntosh JF, Moller E, Van Slyke DD. Studies of urea excretion. III: The Influence of Body Size on Urea Output. The Journal of clinical investigation. 1928;6(3):467-83.
  • 85. Acuna L, Mejia C, Alvis LF, Sanchez P, Soler L. Correlation Between Equation For Estimating Glomerular Filtration Rate: Chronic Kidney Disease Epidemiology Collaboration -Ckd -Epi, Cockcroft-Gault -Cg- And Modification Of Diet And Renal Disease -Mdrd4- In Colombia. Value Health. 2015;18(7):A508.
  • 86. Ballantyne FC, Gibbons J, O’Reilly DS. Urine albumin should replace total protein for the assessment of glomerular proteinuria. Annals of clinical biochemistry. 1993;30 ( Pt 1):101-3.
  • 87. Lamb EJ, MacKenzie F, Stevens PE. How should proteinuria be detected and measured? Annals of clinical biochemistry. 2009;46(Pt 3):205-17.
  • 88. Astor BC, Matsushita K, Gansevoort RT, van der Velde M, Woodward M, Levey AS, et al. Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts. Kidney international. 2011;79(12):1331-40.
  • 89. Hallan SI, Ritz E, Lydersen S, Romundstad S, Kvenild K, Orth SR. Combining GFR and albuminuria to classify CKD improves prediction of ESRD. J Am Soc Nephrol. 2009;20(5):1069-77.
  • 90. Brantsma AH, Bakker SJ, Hillege HL, de Zeeuw D, de Jong PE, Gansevoort RT. Cardiovascular and renal outcome in subjects with K/DOQI stage 1-3 chronic kidney disease: the importance of urinary albumin excretion. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2008;23(12):3851-8.
  • 91. Dawnay A, Wilson AG, Lamb E, Kirby JD, Cattell WR. Microalbuminuria in systemic sclerosis. Annals of the rheumatic diseases. 1992;51(3):384-8.
  • 92. Gross JL, de Azevedo MJ, Silveiro SP, Canani LH, Caramori ML, Zelmanovitz T. Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care. 2005;28(1):164-76.
  • 93. Ninomiya T, Perkovic V, de Galan BE, Zoungas S, Pillai A, Jardine M, et al. Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes. J Am Soc Nephrol. 2009;20(8):1813-21.
  • 94. Shihabi ZK, Konen JC, O’Connor ML. Albuminuria vs urinary total protein for detecting chronic renal disorders. Clinical chemistry. 1991;37(5):621-4.
  • 95. Martin H. Laboratory measurement of urine albumin and urine total protein in screening for proteinuria in chronic kidney disease. The Clinical biochemist Reviews / Australian Association of Clinical Biochemists. 2011;32(2):97-102.
  • 96. Waugh J, Bell SC, Kilby M, Lambert P, Shennan A, Halligan A. Effect of concentration and biochemical assay on the accuracy of urine dipsticks in hypertensive pregnancies. Hypertension in pregnancy. 2001;20(2):205-17.
  • 97. Waugh J, Bell SC, Kilby MD, Lambert P, Shennan A, Halligan A. Urine protein estimation in hypertensive pregnancy: which thresholds and laboratory assay best predict clinical outcome? Hypertension in pregnancy. 2005;24(3):291-302.
  • 98. McElderry LA, Tarbit IF, Cassells-Smith AJ. Six methods for urinary protein compared. Clinical chemistry. 1982;28(2):356-60.
  • 99. Nishi HH, Elin RJ. Three turbidimetric methods for determining total protein compared. Clinical chemistry. 1985;31(8):1377-80.
  • 100. Sedmak JJ, Grossberg SE. A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250. Analytical biochemistry. 1977;79(1-2):544-52.
  • 101. de Keijzer MH, Klasen IS, Branten AJ, Hordijk W, Wetzels JF. Infusion of plasma expanders may lead to unexpected results in urinary protein assays. Scandinavian journal of clinical and laboratory investigation. 1999;59(2):133-7.
  • 102. Marshall T, Williams KM. Extent of aminoglycoside interference in the pyrogallol redmolybdate protein assay depends on the concentration of sodium oxalate in the dye reagent. Clinical chemistry. 2004;50(5):934-5.
  • 103. Yilmaz FM, Yucel D. Effect of addition of hemolysate on urine and cerebrospinal fluid assays for protein. Clinical chemistry. 2006;52(1):152-3.
  • 104. Chambers RE, Bullock DG, Whicher JT. External quality assessment of total urinary protein estimation in the United Kingdom. Annals of clinical biochemistry. 1991;28 ( Pt 5):467-73.
  • 105. Heick HM, Begin-Heick N, Acharya C, Mohammed A. Automated determination of urine and cerebrospinal fluid proteins with Coomassie Brilliant Blue and the Abbott ABA100. Clinical biochemistry. 1980;13(2):81-3.
  • 106. Marshall T, Williams KM. Total protein determination in urine: elimination of a differential response between the coomassie blue and pyrogallol red protein dye-binding assays. Clinical chemistry. 2000;46(3):392-8.
  • 107. Miller WG. Urine albumin: Recommendations for standardization. Scandinavian journal of clinical and laboratory investigation Supplementum. 2008;241:71-2.
  • 108. Parsons M, Newman DJ, Pugia M, Newall RG, Price CP. Performance of a reagent strip device for quantitation of the urine albumin: creatinine ratio in a point of care setting. Clinical nephrology. 1999;51(4):220-7.
  • 109. Parsons MP, Newman DJ, Newall RG, Price CP. Validation of a point-of-care assay for the urinary albumin:creatinine ratio. Clinical chemistry. 1999;45(3):414-7.
  • 110. Medicines and Healthcare products Regulatory Agency, MHRA 04098. Point of care devices for the detection and semi-quantitation of microalbuminuria. . 2004.
  • 111. Graziani MS, Gambaro G, Mantovani L, Sorio A, Yabarek T, Abaterusso C, et al. Diagnostic accuracy of a reagent strip for assessing urinary albumin excretion in the general population. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2009;24(5):1490-4.
  • 112. Guy M, Newall R, Borzomato J, Kalra PA, Price C. Diagnostic accuracy of the urinary albumin: creatinine ratio determined by the CLINITEK Microalbumin and DCA 2000+ for the rule-out of albuminuria in chronic kidney disease. Clinica chimica acta; international journal of clinical chemistry. 2009;399(1-2):54-8.
  • 113. Waugh JJ, Bell SC, Kilby MD, Blackwell CN, Seed P, Shennan AH, et al. Optimal bedside urinalysis for the detection of proteinuria in hypertensive pregnancy: a study of diagnostic accuracy. BJOG : an international journal of obstetrics and gynaecology. 2005;112(4):412-7.
  • 114. Iseki K, Iseki C, Ikemiya Y, Fukiyama K. Risk of developing end-stage renal disease in a cohort of mass screening. Kidney international. 1996;49(3):800-5.
  • 115. Kaplan RE, Springate JE, Feld LG. Screening dipstick urinalysis: a time to change. Pediatrics. 1997;100(6):919-21.
  • 116. Kitagawa T. Lessons learned from the Japanese nephritis screening study. Pediatric nephrology. 1988;2(2):256-63.
  • 117. Boulware LE, Jaar BG, Tarver-Carr ME, Brancati FL, Powe NR. Screening for proteinuria in US adults: a cost-effectiveness analysis. JAMA. 2003;290(23):3101-14.
  • 118. Bowie L, Smith S, Gochman N. Characteristics of binding between reagent-strip indicators and urinary proteins. Clinical chemistry. 1977;23(1):128-30.
  • 119. Gyure WL. Comparison of several methods for semiquantitative determination of urinary protein. Clinical chemistry. 1977;23(5):876-9.
  • 120. James GP, Bee DE, Fuller JB. Proteinuria: accuracy and precision of laboratory diagnosis by dip-stick analysis. Clinical chemistry. 1978;24(11):1934-9.
  • 121. Rumley A. Urine dipstick testing: comparison of results obtained by visual reading and with the Bayer CLINITEK 50. Annals of clinical biochemistry. 2000;37 ( Pt 2):220-1.
  • 122. Scotti da Silva-Colombeli A, Falkenberg M. Analytical interferences of drugs in the chemical examination of urinary protein. Clinical biochemistry. 2007;40(13-14):1074-6.
  • 123. Ralston SH, Caine N, Richards I, O’Reilly D, Sturrock RD, Capell HA. Screening for proteinuria in a rheumatology clinic: comparison of dipstick testing, 24 hour urine quantitative protein, and protein/creatinine ratio in random urine samples. Annals of the rheumatic diseases. 1988;47(9):759-63.
  • 124. Waugh JJ, Clark TJ, Divakaran TG, Khan KS, Kilby MD. Accuracy of urinalysis dipstick techniques in predicting significant proteinuria in pregnancy. Obstetrics and gynecology. 2004;103(4):769-77.
  • 125. White SL, Yu R, Craig JC, Polkinghorne KR, Atkins RC, Chadban SJ. Diagnostic accuracy of urine dipsticks for detection of albuminuria in the general community. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2011;58(1):19-28.
  • 126. Saudan PJ, Brown MA, Farrell T, Shaw L. Improved methods of assessing proteinuria in hypertensive pregnancy. British journal of obstetrics and gynaecology. 1997;104(10):1159-64.
  • 127. Beetham R, Cattell WR. Proteinuria: pathophysiology, significance and recommendations for measurement in clinical practice. Annals of clinical biochemistry. 1993;30 ( Pt 5):425-34.
  • 128. Keane WF, Eknoyan G. Proteinuria, albuminuria, risk, assessment, detection, elimination (PARADE): a position paper of the National Kidney Foundation. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1999;33(5):1004- 10.
  • 129. Miller WG, Bruns DE, Hortin GL, Sandberg S, Aakre KM, McQueen MJ, et al. Current issues in measurement and reporting of urinary albumin excretion. Clinical chemistry. 2009;55(1):24-38.
  • 130. Claudi T, Cooper JG. Comparison of urinary albumin excretion rate in overnight urine and albumin creatinine ratio in spot urine in diabetic patients in general practice. Scandinavian journal of primary health care. 2001;19(4):247-8.
  • 131. Gatling W, Knight C, Mullee MA, Hill RD. Microalbuminuria in diabetes: a population study of the prevalence and an assessment of three screening tests. Diabetic medicine : a journal of the British Diabetic Association. 1988;5(4):343-7.
  • 132. Hutchison AS, O’Reilly DS, MacCuish AC. Albumin excretion rate, albumin concentration, and albumin/creatinine ratio compared for screening diabetics for slight albuminuria. Clinical chemistry. 1988;34(10):2019-21.
  • 133. Marshall SM, Alberti KG. Screening for early diabetic nephropathy. Annals of clinical biochemistry. 1986;23 ( Pt 2):195-7.
  • 134. Marshall SM. Screening for microalbuminuria: which measurement? Diabetic medicine : a journal of the British Diabetic Association. 1991;8(8):706-11.
  • 135. Chitalia VC, Kothari J, Wells EJ, Livesey JH, Robson RA, Searle M, et al. Costbenefit analysis and prediction of 24-hour proteinuria from the spot urine protein-creatinine ratio. Clinical nephrology. 2001;55(6):436-47.
  • 136. Cote AM, Brown MA, Lam E, von Dadelszen P, Firoz T, Liston RM, et al. Diagnostic accuracy of urinary spot protein:creatinine ratio for proteinuria in hypertensive pregnant women: systematic review. Bmj. 2008;336(7651):1003-6.
  • 137. Dyson EH, Will EJ, Davison AM, O’Malley AH, Shepherd HT, Jones RG. Use of the urinary protein creatinine index to assess proteinuria in renal transplant patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 1992;7(5):450-2.
  • 138. Ginsberg JM, Chang BS, Matarese RA, Garella S. Use of single voided urine samples to estimate quantitative proteinuria. The New England journal of medicine. 1983;309(25):1543-6.
  • 139. Leanos-Miranda A, Marquez-Acosta J, Romero-Arauz F, Cardenas-Mondragon GM, Rivera-Leanos R, Isordia-Salas I, et al. Protein: creatinine ratio in random urine samples is a reliable marker of increased 24-hour protein excretion in hospitalized women with hypertensive disorders of pregnancy. Clinical chemistry. 2007;53(9):1623-8.
  • 140. Lemann J, Jr., Doumas BT. Proteinuria in health and disease assessed by measuring the urinary protein/creatinine ratio. Clinical chemistry. 1987;33(2 Pt 1):297-9.
  • 141. Ruggenenti P, Gaspari F, Perna A, Remuzzi G. Cross sectional longitudinal study of spot morning urine protein:creatinine ratio, 24 hour urine protein excretion rate, glomerular filtration rate, and end stage renal failure in chronic renal disease in patients without diabetes. Bmj. 1998;316(7130):504-9.
  • 142. Pugliese G, Solini A, Fondelli C, Trevisan R, Vedovato M, Nicolucci A, et al. Reproducibility of albuminuria in type 2 diabetic subjects. Findings from the Renal Insufficiency And Cardiovascular Events (RIACE) study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2011;26(12):3950-4.
  • 143. Newman DJ, Pugia MJ, Lott JA, Wallace JF, Hiar AM. Urinary protein and albumin excretion corrected by creatinine and specific gravity. Clinica chimica acta; international journal of clinical chemistry. 2000;294(1-2):139-55.
  • 144. Howey JE, Browning MC, Fraser CG. Selecting the optimum specimen for assessing slight albuminuria, and a strategy for clinical investigation: novel uses of data on biological variation. Clinical chemistry. 1987;33(11):2034-8.
  • 145. Carter JL, Tomson CR, Stevens PE, Lamb EJ. Does urinary tract infection cause proteinuria or microalbuminuria? A systematic review. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2006;21(11):3031-7.
  • 146. Heathcote KL, Wilson MP, Quest DW, Wilson TW. Prevalence and duration of exercise induced albuminuria in healthy people. Clinical and investigative medicine Medecine clinique et experimentale. 2009;32(4):E261-5.
  • 147. Vehaskari VM. Orthostatic proteinuria. Archives of disease in childhood. 1982;57(10):729-30.
  • 148. Leung AK, Wong AH. Proteinuria in children. American family physician. 2010;82(6):645-51.
  • 149. Boger CA, Chen MH, Tin A, Olden M, Kottgen A, de Boer IH, et al. CUBN is a gene locus for albuminuria. J Am Soc Nephrol. 2011;22(3):555-70.
  • 150. Montanes Bermudez R, Gracia Garcia S, Perez Surribas D, Martinez Castelao A, Bover Sanjuan J. Consensus document. Recommendations on assessing proteinuria during the diagnosis and follow-up of chronic kidney disease. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia. 2011;31(3):331-45.
  • 151. Lamb EJ, Price CP. Kidney function tests. In: Burtis CA, Ashwood E, Bruns DE, editors. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics,. 5th ed. Bruns, DE. : Elsevier; 2012. p. 669-708.
  • 152. National Institute for Health and Clinical Excellence. NICE clinical guideline 73. Chronic kidney disease: early identification and management of chronic kidney disease in adults in primary and secondary care. 2008.
  • 153. Panek R, Lawen T, Kiberd BA. Screening for proteinuria in kidney transplant recipients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2011;26(4):1385-7.
  • 154. Incerti J, Zelmanovitz T, Camargo JL, Gross JL, de Azevedo MJ. Evaluation of tests for microalbuminuria screening in patients with diabetes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2005;20(11):2402-7.
  • 155. Methven S, MacGregor MS, Traynor JP, O’Reilly DS, Deighan CJ. Assessing proteinuria in chronic kidney disease: protein-creatinine ratio versus albumin-creatinine ratio. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2010;25(9):2991-6.
  • 156. Methven S, MacGregor MS, Traynor JP, Hair M, O’Reilly DS, Deighan CJ. Comparison of urinary albumin and urinary total protein as predictors of patient outcomes in CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2011;57(1):21-8.
  • 157. Methven S, Traynor JP, Hair MD, St JORD, Deighan CJ, MacGregor MS. Stratifying risk in chronic kidney disease: an observational study of UK guidelines for measuring total proteinuria and albuminuria. QJM : monthly journal of the Association of Physicians. 2011;104(8):663-70.
  • 158. Nauta FL, Bakker SJ, van Oeveren W, Navis G, van der Heide JJ, van Goor H, et al. Albuminuria, proteinuria, and novel urine biomarkers as predictors of long-term allograft outcomes in kidney transplant recipients. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2011;57(5):733-43.
  • 159. Ellam TJ. Albumin: creatinine ratio-a flawed measure? The merits of estimated albuminuria reporting. Nephron Clinical practice. 2011;118(4):c324-30.
  • 160. Comper WD, Osicka TM, Clark M, MacIsaac RJ, Jerums G. Earlier detection of microalbuminuria in diabetic patients using a new urinary albumin assay. Kidney international. 2004;65(5):1850-5.
  • 161. Comper WD, Osicka TM, Jerums G. High prevalence of immuno-unreactive intact albumin in urine of diabetic patients. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2003;41(2):336-42.
  • 162. Magliano DJ, Polkinghorne KR, Barr EL, Su Q, Chadban SJ, Zimmet PZ, et al. HPLCdetected albuminuria predicts mortality. J Am Soc Nephrol. 2007;18(12):3171-6.
  • 163. Osicka TM, Comper WD. Characterization of immunochemically nonreactive urinary albumin. Clinical chemistry. 2004;50(12):2286-91.
  • 164. Sviridov D, Drake SK, Hortin GL. Reactivity of urinary albumin (microalbumin) assays with fragmented or modified albumin. Clinical chemistry. 2008;54(1):61-8.
  • 165. Sviridov D, Meilinger B, Drake SK, Hoehn GT, Hortin GL. Coelution of other proteins with albumin during size-exclusion HPLC: Implications for analysis of urinary albumin. Clinical chemistry. 2006;52(3):389-97.
  • 166. Wrong OM, Norden AG, Feest TG. Dent’s disease; a familial proximal renal tubular syndrome with low-molecular-weight proteinuria, hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive renal failure and a marked male predominance. QJM : monthly journal of the Association of Physicians. 1994;87(8):473-93.
  • 167. Atkins RC, Briganti EM, Zimmet PZ, Chadban SJ. Association between albuminuria and proteinuria in the general population: the AusDiab Study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2003;18(10):2170-4.
  • 168. Gosling P. Proteinuria. In: Marshall WJ, Bangert SK, editors. Clinical Biochemistry: Metabolic and Clinical Aspects. 2nd ed: Elsevier; 2008. p. 156-73.
  • 169. Goren MP, Li JT. The Coomassie Brilliant Blue method underestimates drug-induced tubular proteinuria. Clinical chemistry. 1986;32(2):386-8.
  • 170. Weber MH, Verwiebe R. Alpha 1-microglobulin (protein HC): features of a promising indicator of proximal tubular dysfunction. European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies. 1992;30(10):683-91.
  • 171. Ginevri F, Piccotti E, Alinovi R, DeToni T, Biagini C, Chiggeri GM, et al. Reversible tubular proteinuria precedes microalbuminuria and correlates with the metabolic status in diabetic children. Pediatric nephrology. 1993;7(1):23-6.
  • 172. Tomlinson PA, Smellie JM, Prescod N, Dalton RN, Chantler C. Differential excretion of urinary proteins in children with vesicoureteric reflux and reflux nephropathy. Pediatric nephrology. 1994;8(1):21-5.
  • 173. Bird JM, Owen RG, D’Sa S, Snowden JA, Pratt G, Ashcroft J, et al. Guidelines for the diagnosis and management of multiple myeloma 2011. British journal of haematology. 2011;154(1):32-75.
  • 174. Slack TK, Wilson DM. Normal renal function: CIN and CPAH in healthy donors before and after nephrectomy. Mayo Clinic proceedings. 1976;51(5):296-300.
  • 175. Rowe JW, Andres R, Tobin JD, Norris AH, Shock NW. The effect of age on creatinine clearance in men: a cross-sectional and longitudinal study. Journal of gerontology. 1976;31(2):155-63.
  • 176. Lindeman RD, Tobin JD, Shock NW. Association between blood pressure and the rate of decline in renal function with age. Kidney international. 1984;26(6):861-8.
  • 177. Halbesma N, Kuiken DS, Brantsma AH, Bakker SJ, Wetzels JF, De Zeeuw D, et al. Macroalbuminuria is a better risk marker than low estimated GFR to identify individuals at risk for accelerated GFR loss in population screening. J Am Soc Nephrol. 2006;17(9):2582- 90.
  • 178. 1. Halbesma N KD, Brantsma AH et al. Macroalbuminuria is a better risk marker than low estimated GFR to identify individuals at risk for accelerated GFR loss in population screening. J Am Soc Nephrol 2006;17:2582–90.
  • 179. Matsushita K, Selvin E, Bash LD, Franceschini N, Astor BC, Coresh J. Change in estimated GFR associates with coronary heart disease and mortality. J Am Soc Nephrol. 2009;20(12):2617-24.
  • 180. Kronborg J, Solbu M, Njolstad I, Toft I, Eriksen BO, Jenssen T. Predictors of change in estimated GFR: a population-based 7-year follow-up from the Tromso study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2008;23(9):2818-26.
  • 181. Imai E, Horio M, Yamagata K, Iseki K, Hara S, Ura N, et al. Slower decline of glomerular filtration rate in the Japanese general population: a longitudinal 10-year follow- up study. Hypertension research : official journal of the Japanese Society of Hypertension. 2008;31(3):433-41.
  • 182. Hemmelgarn BR, Zhang J, Manns BJ, Tonelli M, Larsen E, Ghali WA, et al. Progression of kidney dysfunction in the community-dwelling elderly. Kidney international. 2006;69(12):2155-61.
  • 183. Keller C, Katz R, Sarnak MJ, Fried LF, Kestenbaum B, Cushman M, et al. Inflammatory biomarkers and decline in kidney function in the elderly: the Cardiovascular Health Study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2010;25(1):119-24.
  • 184. John R, Webb M, Young A, Stevens PE. Unreferred chronic kidney disease: a longitudinal study. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2004;43(5):825-35.
  • 185. Levey AS, Gassman JJ, Hall PM, Walker WG. Assessing the progression of renal disease in clinical studies: effects of duration of follow-up and regression to the mean. Modification of Diet in Renal Disease (MDRD) Study Group. J Am Soc Nephrol. 1991;1(9):1087-94.
  • 186. Klahr S, Levey AS, Beck GJ, Caggiula AW, Hunsicker L, Kusek JW, et al. The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of Diet in Renal Disease Study Group. The New England journal of medicine. 1994;330(13):877-84.
  • 187. Wright JT, Jr., Bakris G, Greene T, Agodoa LY, Appel LJ, Charleston J, et al. Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. JAMA. 2002;288(19):2421-31.
  • 188. Eriksen BO, Ingebretsen OC. The progression of chronic kidney disease: a 10-year population-based study of the effects of gender and age. Kidney international. 2006;69(2):375-82.
  • 189. Jones C, Roderick P, Harris S, Rogerson M. Decline in kidney function before and after nephrology referral and the effect on survival in moderate to advanced chronic kidney disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2006;21(8):2133-43.
  • 190. Levin A, Djurdjev O, Beaulieu M, Er L. Variability and risk factors for kidney disease progression and death following attainment of stage 4 CKD in a referred cohort. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2008;52(4):661-71.
  • 191. Al-Aly Z, Zeringue A, Fu J, Rauchman MI, McDonald JR, El-Achkar TM, et al. Rate of kidney function decline associates with mortality. J Am Soc Nephrol. 2010;21(11):1961- 9.
  • 192. Shlipak MG, Katz R, Kestenbaum B, Siscovick D, Fried L, Newman A, et al. Rapid decline of kidney function increases cardiovascular risk in the elderly. J Am Soc Nephrol. 2009;20(12):2625-30.
  • 193. Rifkin DE, Shlipak MG, Katz R, Fried LF, Siscovick D, Chonchol M, et al. Rapid kidney function decline and mortality risk in older adults. Archives of internal medicine. 2008;168(20):2212-8.
  • 194. Cheng TY, Wen SF, Astor BC, Tao XG, Samet JM, Wen CP. Mortality risks for all causes and cardiovascular diseases and reduced GFR in a middle-aged working population in Taiwan. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2008;52(6):1051-60.
  • 195. National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2002;39:S1–266.
  • 196. Appel LJ, Wright JT, Jr., Greene T, Agodoa LY, Astor BC, Bakris GL, et al. Intensive blood-pressure control in hypertensive chronic kidney disease. The New England journal of medicine. 2010;363(10):918-29.
  • 197. Hunsicker LG, Adler S, Caggiula A, England BK, Greene T, Kusek JW, et al. Predictors of the progression of renal disease in the Modification of Diet in Renal Disease Study. Kidney international. 1997;51(6):1908-19.
  • 198. Menon V, Wang X, Sarnak MJ, Hunsicker LH, Madero M, Beck GJ, et al. Long-term outcomes in nondiabetic chronic kidney disease. Kidney international. 2008;73(11):1310-5.
  • 199. Adler AI, Stevens RJ, Manley SE, Bilous RW, Cull CA, Holman RR. Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64). Kidney international. 2003;63(1):225-32.
  • 200. Caramori ML, Fioretto P, Mauer M. Enhancing the predictive value of urinary albumin for diabetic nephropathy. J Am Soc Nephrol. 2006;17(2):339-52.
  • 201. Hoefield RA, Kalra PA, Baker PG, Sousa I, Diggle PJ, Gibson MJ, et al. The use of eGFR and ACR to predict decline in renal function in people with diabetes. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2011;26(3):887-92.
  • 202. Rosolowsky ET, Skupien J, Smiles AM, Niewczas M, Roshan B, Stanton R, et al. Risk for ESRD in type 1 diabetes remains high despite renoprotection. J Am Soc Nephrol. 2011;22(3):545-53.
  • 203. Hemmelgarn BR, Clement F, Manns BJ, Klarenbach S, James MT, Ravani P, et al. Overview of the Alberta Kidney Disease Network. BMC nephrology. 2009;10:30.
  • 204. Turin TC, Coresh J, Tonelli M, Stevens PE, de Jong PE, Farmer CK, et al. One-year change in kidney function is associated with an increased mortality risk. American journal of nephrology. 2012;36(1):41-9.
  • 205. Turin TC, Coresh J, Tonelli M, Stevens PE, de Jong PE, Farmer CK, et al. Shortterm change in kidney function and risk of end-stage renal disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2012;27(10):3835-43.
  • 206. Schmieder RE, Mann JF, Schumacher H, Gao P, Mancia G, Weber MA, et al. Changes in albuminuria predict mortality and morbidity in patients with vascular disease. J Am Soc Nephrol. 2011;22(7):1353-64.
  • 207. Li L, Astor BC, Lewis J, Hu B, Appel LJ, Lipkowitz MS, et al. Longitudinal progression trajectory of GFR among patients with CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2012;59(4):504-12.
  • 208. O’Hare AM, Batten A, Burrows NR, Pavkov ME, Taylor L, Gupta I, et al. Trajectories of kidney function decline in the 2 years before initiation of long-term dialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2012;59(4):513-22.
  • 209. Leblanc M, Kellum JA, Gibney RT, Lieberthal W, Tumlin J, Mehta R. Risk factors for acute renal failure: inherent and modifiable risks. Current opinion in critical care. 2005;11(6):533-6.
  • 210. Naughton CA. Drug-induced nephrotoxicity. American family physician. 2008;78(6):743-50.
  • 211. Pannu N, Nadim MK. An overview of drug-induced acute kidney injury. Critical care medicine. 2008;36(4 Suppl):S216-23.
  • 212. Solomon R, Dauerman HL. Contrast-induced acute kidney injury. Circulation. 2010;122(23):2451-5.
  • 213. Black C, Sharma P, Scotland G, McCullough K, McGurn D, Robertson L, et al. Early referral strategies for management of people with markers of renal disease: a systematic review of the evidence of clinical effectiveness, cost-effectiveness and economic analysis. Health technology assessment (Winchester, England). 2010;14(21):1-184.
  • 214. Bang H, Mazumdar M, Newman G, Bomback AS, Ballantyne CM, Jaffe AS, et al. Screening for kidney disease in vascular patients: SCreening for Occult REnal Disease (SCORED) experience. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2009;24(8):2452-7.
  • 215. Johnson ES, Smith DH, Thorp ML, Yang X, Juhaeri J. Predicting the risk of endstage renal disease in the population-based setting: a retrospective case-control study. BMC nephrology. 2011;12:17.
  • 216. Wakai K, Kawamura T, Endoh M, Kojima M, Tomino Y, Tamakoshi A, et al. A scoring system to predict renal outcome in IgA nephropathy: from a nationwide prospective study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2006;21(10):2800-8.
  • 217. Keane WF, Zhang Z, Lyle PA, Cooper ME, de Zeeuw D, Grunfeld JP, et al. Risk scores for predicting outcomes in patients with type 2 diabetes and nephropathy: the RENAAL study. Clinical journal of the American Society of Nephrology : CJASN. 2006;1(4):761-7.
  • 218. Fine EJ, Blaufox MD. Prediction rule for renal artery stenosis. Annals of internal medicine. 1999;131(3):227-8.
  • 219. Kshirsagar AV, Bang H, Bomback AS, Vupputuri S, Shoham DA, Kern LM, et al. A simple algorithm to predict incident kidney disease. Archives of internal medicine. 2008;168(22):2466-73.
  • 220. Tangri N, Stevens LA, Griffith J, Tighiouart H, Djurdjev O, Naimark D, et al. A predictive model for progression of chronic kidney disease to kidney failure. JAMA. 2011;305(15):1553-9.
  • 221. Halbesma N, Jansen DF, Heymans MW, Stolk RP, de Jong PE, Gansevoort RT. Development and validation of a general population renal risk score. Clinical journal of the American Society of Nephrology : CJASN. 2011;6(7):1731-8.
  • 222. KDIGO GN Work Group. KDIGO clinical practice guideline for glomerulonephritis. Kidney inter. 2012;2:139–274.
  • 223. National Kidney Foundation. KDOQI Clinical Practice Guideline for Diabetes and CKD: 2012 Update. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2012;60(5):850-86.
  • 224. KDIGO BP Work Group. KDIGO clinical practice guideline for the management of blood pressure in chronic kidney disease. Kidney inter. 2012;2:337-414.
  • 225. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, et al. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA. 2005;294(7):813-8.
  • 226. Mittalhenkle A, Stehman-Breen CO, Shlipak MG, Fried LF, Katz R, Young BA, et al. Cardiovascular risk factors and incident acute renal failure in older adults: the cardiovascular health study. Clinical journal of the American Society of Nephrology : CJASN. 2008;3(2):450-6.
  • 227. Hoste EA, Lameire NH, Vanholder RC, Benoit DD, Decruyenaere JM, Colardyn FA. Acute renal failure in patients with sepsis in a surgical ICU: predictive factors, incidence, comorbidity, and outcome. J Am Soc Nephrol. 2003;14(4):1022-30.
  • 228. McCullough PA, Wolyn R, Rocher LL, Levin RN, O’Neill WW. Acute renal failure after coronary intervention: incidence, risk factors, and relationship to mortality. The American journal of medicine. 1997;103(5):368-75.
  • 229. Mehran R, Aymong ED, Nikolsky E, Lasic Z, Iakovou I, Fahy M, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. Journal of the American College of Cardiology. 2004;44(7):1393-9.
  • 230. Mehta RH, Grab JD, O’Brien SM, Bridges CR, Gammie JS, Haan CK, et al. Bedside tool for predicting the risk of postoperative dialysis in patients undergoing cardiac surgery. Circulation. 2006;114(21):2208-16; quiz
  • 231. Thakar CV, Worley S, Arrigain S, Yared JP, Paganini EP. Influence of renal dysfunction on mortality after cardiac surgery: modifying effect of preoperative renal function. Kidney international. 2005;67(3):1112-9.
  • 232. Waikar SS, Liu KD, Chertow GM. Diagnosis, epidemiology and outcomes of acute kidney injury. Clinical journal of the American Society of Nephrology : CJASN. 2008;3(3):844-61.
  • 233. Yegenaga I, Hoste E, Van Biesen W, Vanholder R, Benoit D, Kantarci G, et al. Clinical characteristics of patients developing ARF due to sepsis/systemic inflammatory response syndrome: results of a prospective study. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2004;43(5):817-24.
  • 234. Browner WS, Li J, Mangano DT. In-hospital and long-term mortality in male veterans following noncardiac surgery. The Study of Perioperative Ischemia Research Group. JAMA. 1992;268(2):228-32.
  • 235. Hou SH, Bushinsky DA, Wish JB, Cohen JJ, Harrington JT. Hospital-acquired renal insufficiency: a prospective study. The American journal of medicine. 1983;74(2):243-8.
  • 236. Singh P, Rifkin DE, Blantz RC. Chronic kidney disease: an inherent risk factor for acute kidney injury? Clinical journal of the American Society of Nephrology : CJASN. 2010;5(9):1690-5.
  • 237. Lafrance JP, Djurdjev O, Levin A. Incidence and outcomes of acute kidney injury in a referred chronic kidney disease cohort. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2010;25(7):2203-9.
  • 238. Chertow GM, Christiansen CL, Cleary PD, Munro C, Lazarus JM. Prognostic stratification in critically ill patients with acute renal failure requiring dialysis. Archives of internal medicine. 1995;155(14):1505-11.
  • 239. Chertow GM, Soroko SH, Paganini EP, Cho KC, Himmelfarb J, Ikizler TA, et al. Mortality after acute renal failure: models for prognostic stratification and risk adjustment. Kidney international. 2006;70(6):1120-6.
  • 240. Mehta RL, Pascual MT, Gruta CG, Zhuang S, Chertow GM. Refining predictive models in critically ill patients with acute renal failure. J Am Soc Nephrol. 2002;13(5):1350- 7.
  • 241. Paganini EP, Larive B, Kanagasundaram NS. Severity scores and outcomes with acute renal failure in the ICU setting. Contributions to nephrology. 2001(132):181-95.
  • 242. Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, et al. External validation of severity scoring systems for acute renal failure using a multinational database. Critical care medicine. 2005;33(9):1961-7.
  • 243. Waikar SS, Curhan GC, Wald R, McCarthy EP, Chertow GM. Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol. 2006;17(4):1143-50.
  • 244. Khosla N, Soroko SB, Chertow GM, Himmelfarb J, Ikizler TA, Paganini E, et al. Preexisting chronic kidney disease: a potential for improved outcomes from acute kidney injury. Clinical journal of the American Society of Nephrology : CJASN. 2009;4(12):1914-9.
  • 245. Fouque D, Laville M. Low protein diets for chronic kidney disease in non diabetic adults. The Cochrane database of systematic reviews. 2009(3):CD001892.
  • 246. Fouque D, Laville M, Boissel JP, Chifflet R, Labeeuw M, Zech PY. Controlled low protein diets in chronic renal insufficiency: meta-analysis. Bmj. 1992;304(6821):216-20.
  • 247. Kasiske BL, Lakatua JD, Ma JZ, Louis TA. A meta-analysis of the effects of dietary protein restriction on the rate of decline in renal function. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1998;31(6):954-61.
  • 248. Pedrini MT, Levey AS, Lau J, Chalmers TC, Wang PH. The effect of dietary protein restriction on the progression of diabetic and nondiabetic renal diseases: a meta-analysis. Annals of internal medicine. 1996;124(7):627-32.
  • 249. Robertson L, Waugh N, Robertson A. Protein restriction for diabetic renal disease. The Cochrane database of systematic reviews. 2007(4):CD002181.
  • 250. Menon V, Kopple JD, Wang X, Beck GJ, Collins AJ, Kusek JW, et al. Effect of a very low-protein diet on outcomes: long-term follow-up of the Modification of Diet in Renal Disease (MDRD) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2009;53(2):208-17.
  • 251. Knight EL, Stampfer MJ, Hankinson SE, Spiegelman D, Curhan GC. The impact of protein intake on renal function decline in women with normal renal function or mild renal insufficiency. Annals of internal medicine. 2003;138(6):460-7.
  • 252. Patel A, MacMahon S, Chalmers J, Neal B, Billot L, Woodward M, et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. The New England journal of medicine. 2008;358(24):2560-72.
  • 253. Ismail-Beigi F, Craven T, Banerji MA, Basile J, Calles J, Cohen RM, et al. Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet. 2010;376(9739):419-30.
  • 254. Duckworth W, Abraira C, Moritz T, Reda D, Emanuele N, Reaven PD, et al. Glucose control and vascular complications in veterans with type 2 diabetes. The New England journal of medicine. 2009;360(2):129-39.
  • 255. Nathan DM, Zinman B, Cleary PA, Backlund JY, Genuth S, Miller R, et al. Modernday clinical course of type 1 diabetes mellitus after 30 years’ duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005). Archives of internal medicine. 2009;169(14):1307-16.
  • 256. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet. 1998;352(9131):837-53.
  • 257. Ichikawa H, Nagake Y, Takahashi M, Nakazono H, Kawabata K, Shikata K, et al. What is the best index of glycemic control in patients with diabetes mellitus on hemodialysis? Nihon Jinzo Gakkai shi. 1996;38(7):305-8.
  • 258. Joy MS, Cefalu WT, Hogan SL, Nachman PH. Long-term glycemic control measurements in diabetic patients receiving hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2002;39(2):297-307.
  • 259. Nakao T, Matsumoto H, Okada T, Han M, Hidaka H, Yoshino M, et al. Influence of erythropoietin treatment on hemoglobin A1c levels in patients with chronic renal failure on hemodialysis. Intern Med. 1998;37(10):826-30.
  • 260. Ng JM, Cooke M, Bhandari S, Atkin SL, Kilpatrick ES. The effect of iron and erythropoietin treatment on the A1C of patients with diabetes and chronic kidney disease. Diabetes Care. 2010;33(11):2310-3.
  • 261. Shima K, Chujo K, Yamada M, Komatsu M, Noma Y, Mizuguchi T. Lower value of glycated haemoglobin relative to glycaemic control in diabetic patients with end-stage renal disease not on haemodialysis. Annals of clinical biochemistry. 2012;49(Pt 1):68-74.
  • 262. Vos FE, Schollum JB, Coulter CV, Manning PJ, Duffull SB, Walker RJ. Assessment of markers of glycaemic control in diabetic patients with chronic kidney disease using continuous glucose monitoring. Nephrology. 2012;17(2):182-8.
  • 263. Jones-Burton C, Mishra SI, Fink JC, Brown J, Gossa W, Bakris GL, et al. An in-depth review of the evidence linking dietary salt intake and progression of chronic kidney disease. American journal of nephrology. 2006;26(3):268-75.
  • 264. Swift PA, Markandu ND, Sagnella GA, He FJ, MacGregor GA. Modest salt reduction reduces blood pressure and urine protein excretion in black hypertensives: a randomized control trial. Hypertension. 2005;46(2):308-12.
  • 265. Hoffmann IS, Cubeddu LX. Increased blood pressure reactivity to dietary salt in patients with the metabolic syndrome. Journal of human hypertension. 2007;21(6):438-44.
  • 266. Bellizzi V, Di Iorio BR, De Nicola L, Minutolo R, Zamboli P, Trucillo P, et al. Very low protein diet supplemented with ketoanalogs improves blood pressure control in chronic kidney disease. Kidney international. 2007;71(3):245-51.
  • 267. Slagman MC, Waanders F, Hemmelder MH, Woittiez AJ, Janssen WM, Lambers Heerspink HJ, et al. Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial. Bmj. 2011;343:d4366.
  • 268. Kanji T, Gandhi M, Clase CM, Yang R. Urate lowering therapy to improve renal outcomes in patients with chronic kidney disease: systematic review and meta-analysis. BMC nephrology. 2015;16:58.
  • 269. Zhang Y-f, He F, Ding H-h, Dai W, Zhang Q, Luan H, et al. Effect of uric-acid-lowering therapy on progression of chronic kidney disease: a meta-analysis. J Huazhong Univ Sci Technolog Med Sci. 2014;34(4):476-81.
  • 270. Sircar D, Chatterjee S, Waikhom R, Golay V, Raychaudhury A, Chatterjee S, et al. Efficacy of Febuxostat for Slowing the GFR Decline in Patients With CKD and Asymptomatic Hyperuricemia: A 6-Month, Double-Blind, Randomized, Placebo-Controlled Trial. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2015;66(6):945-50.
  • 271. Tanaka K, Nakayama M, Kanno M, Kimura H, Watanabe K, Tani Y, et al. Renoprotective effects of febuxostat in hyperuricemic patients with chronic kidney disease: a parallel-group, randomized, controlled trial. Clinical and Experimental Nephrology. 2015;19(6):1044-53.
  • 272. Tanaka K, Nakayama M, Kanno M, Kimura H, Watanabe K, Tani Y, et al. Renoprotective effects of febuxostat in hyperuricemic patients with chronic kidney disease: a parallel-group, randomized, controlled trial. Clinical and experimental nephrology. 2015;19(6):1044-53.
  • 273. Johansen KL. Exercise and chronic kidney disease: current recommendations. Sports medicine (Auckland, NZ). 2005;35(6):485-99.
  • 274. Johansen KL, Chertow GM, Ng AV, Mulligan K, Carey S, Schoenfeld PY, et al. Physical activity levels in patients on hemodialysis and healthy sedentary controls. Kidney international. 2000;57(6):2564-70.
  • 275. Padilla J, Krasnoff J, Da Silva M, Hsu CY, Frassetto L, Johansen KL, et al. Physical functioning in patients with chronic kidney disease. Journal of nephrology. 2008;21(4):550- 9.
  • 276. Beddhu S, Baird BC, Zitterkoph J, Neilson J, Greene T. Physical activity and mortality in chronic kidney disease (NHANES III). Clinical journal of the American Society of Nephrology : CJASN. 2009;4(12):1901-6.
  • 277. Churchill DN, Torrance GW, Taylor DW, Barnes CC, Ludwin D, Shimizu A, et al. Measurement of quality of life in end-stage renal disease: the time trade-off approach. Clinical and investigative medicine Medecine clinique et experimentale. 1987;10(1):14-20.
  • 278. DeOreo PB. Hemodialysis patient-assessed functional health status predicts continued survival, hospitalization, and dialysis-attendance compliance. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1997;30(2):204-12.
  • 279. Booth FW, Gordon SE, Carlson CJ, Hamilton MT. Waging war on modern chronic diseases: primary prevention through exercise biology. Journal of applied physiology (Bethesda, Md : 1985). 2000;88(2):774-87.
  • 280. Dickinson HO, Mason JM, Nicolson DJ, Campbell F, Beyer FR, Cook JV, et al. Lifestyle interventions to reduce raised blood pressure: a systematic review of randomized controlled trials. Journal of hypertension. 2006;24(2):215-33.
  • 281. Stewart KJ. Exercise training and the cardiovascular consequences of type 2 diabetes and hypertension: plausible mechanisms for improving cardiovascular health. JAMA. 2002;288(13):1622-31.
  • 282. Daul AE, Schafers RF, Daul K, Philipp T. Exercise during hemodialysis. Clinical nephrology. 2004;61 Suppl 1:S26-30.
  • 283. Deligiannis A. Cardiac adaptations following exercise training in hemodialysis patients. Clinical nephrology. 2004;61 Suppl 1:S39-45.
  • 284. Liu S, Yeh S, hemodialysis. Eoeto, 129–142. JotFMA. Effect of exercise training on hemodialysis. J Formos Med Assoc. 2002;6:129-42.
  • 285. Mustata S, Chan C, Lai V, Miller JA. Impact of an exercise program on arterial stiffness and insulin resistance in hemodialysis patients. J Am Soc Nephrol. 2004;15(10):2713-8.
  • 286. Ouzouni S, Kouidi E, Sioulis A, Grekas D, Deligiannis A. Effects of intradialytic exercise training on health-related quality of life indices in haemodialysis patients. Clinical rehabilitation. 2009;23(1):53-63.
  • 287. Storer TW, Casaburi R, Sawelson S, Kopple JD. Endurance exercise training during haemodialysis improves strength, power, fatigability and physical performance in maintenance haemodialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2005;20(7):1429-37.
  • 288. Vaitkevicius PV, Fleg JL, Engel JH, O’Connor FC, Wright JG, Lakatta LE, et al. Effects of age and aerobic capacity on arterial stiffness in healthy adults. Circulation. 1993;88(4 Pt 1):1456-62.
  • 289. Mustata S, Groeneveld S, Davidson W, Ford G, Kiland K, Manns B. Effects of exercise training on physical impairment, arterial stiffness and health-related quality of life in patients with chronic kidney disease: a pilot study. International urology and nephrology. 2011;43(4):1133-41.
  • 290. Szromba C, Thies MA, Ossman SS. Advancing chronic kidney disease care: new imperatives for recognition and intervention. Nephrology nursing journal : journal of the American Nephrology Nurses’ Association. 2002;29(6):547-59; quiz 60-1.
  • 291. Kosmadakis GC, John SG, Clapp EL, Viana JL, Smith AC, Bishop NC, et al. Benefits of regular walking exercise in advanced pre-dialysis chronic kidney disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2012;27(3):997-1004.
  • 292. Hall JE, Crook ED, Jones DW, Wofford MR, Dubbert PM. Mechanisms of obesityassociated cardiovascular and renal disease. The American journal of the medical sciences. 2002;324(3):127-37.
  • 293. Wahba IM, Mak RH. Obesity and obesity-initiated metabolic syndrome: mechanistic links to chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN. 2007;2(3):550-62.
  • 294. Wang Y, Chen X, Song Y, Caballero B, Cheskin LJ. Association between obesity and kidney disease: a systematic review and meta-analysis. Kidney international. 2008;73(1):19-33.
  • 295. Mohsen A, Brown R, Hoefield R, Kalra PA, O’Donoghue D, Middleton R, et al. Body mass index has no effect on rate of progression of chronic kidney disease in subjects with type 2 diabetes mellitus. Journal of nephrology. 2012;25(3):384-93.
  • 296. Hobbs H, Farmer C, Irving J, Klebe B, Stevens P. Is high body mass index independently associated with diminished glomerular filtration rate? An epidemiological study. Journal of renal care. 2011;37(3):148-54.
  • 297. Burton JO, Gray LJ, Webb DR, Davies MJ, Khunti K, Crasto W, et al. Association of anthropometric obesity measures with chronic kidney disease risk in a non-diabetic patient population. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2012;27(5):1860-6.
  • 298. Kasiske BL, Napier J. Glomerular sclerosis in patients with massive obesity. American journal of nephrology. 1985;5(1):45-50.
  • 299. Hsu CY, McCulloch CE, Iribarren C, Darbinian J, Go AS. Body mass index and risk for end-stage renal disease. Annals of internal medicine. 2006;144(1):21-8.
  • 300. Navaneethan SD, Yehnert H, Moustarah F, Schreiber MJ, Schauer PR, Beddhu S. Weight loss interventions in chronic kidney disease: a systematic review and meta-analysis. Clinical journal of the American Society of Nephrology : CJASN. 2009;4(10):1565-74.
  • 301. Afshinnia F, Wilt TJ, Duval S, Esmaeili A, Ibrahim HN. Weight loss and proteinuria: systematic review of clinical trials and comparative cohorts. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2010;25(4):1173-83.
  • 302. Orth SR, Hallan SI. Smoking: a risk factor for progression of chronic kidney disease and for cardiovascular morbidity and mortality in renal patients–absence of evidence or evidence of absence? Clinical journal of the American Society of Nephrology : CJASN. 2008;3(1):226-36.
  • 303. Jungers P, Massy ZA, Nguyen Khoa T, Fumeron C, Labrunie M, Lacour B, et al. Incidence and risk factors of atherosclerotic cardiovascular accidents in predialysis chronic renal failure patients: a prospective study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 1997;12(12):2597-602.
  • 304. Muntner P, He J, Astor BC, Folsom AR, Coresh J. Traditional and nontraditional risk factors predict coronary heart disease in chronic kidney disease: results from the atherosclerosis risk in communities study. J Am Soc Nephrol. 2005;16(2):529-38.
  • 305. Myllymaki J, Syrjanen J, Helin H, Pasternack A, Kattainen A, Mustonen J. Vascular diseases and their risk factors in IgA nephropathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2006;21(7):1876-82.
  • 306. Shlipak MG, Fried LF, Cushman M, Manolio TA, Peterson D, Stehman-Breen C, et al. Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors. JAMA. 2005;293(14):1737-45.
  • 307. Chase HP, Garg SK, Marshall G, Berg CL, Harris S, Jackson WE, et al. Cigarette smoking increases the risk of albuminuria among subjects with type I diabetes. JAMA. 1991;265(5):614-7.
  • 308. Gambaro G, Bax G, Fusaro M, Normanno M, Manani SM, Zanella M, et al. Cigarette smoking is a risk factor for nephropathy and its progression in type 2 diabetes mellitus. Diabetes, nutrition & metabolism. 2001;14(6):337-42.
  • 309. Hallan SI, Orth SR. Smoking is a risk factor in the progression to kidney failure. Kidney international. 2011;80(5):516-23.
  • 310. Sawicki PT, Didjurgeit U, Muhlhauser I, Bender R, Heinemann L, Berger M. Smoking is associated with progression of diabetic nephropathy. Diabetes Care. 1994;17(2):126-31.
  • 311. Sung RS, Althoen M, Howell TA, Ojo AO, Merion RM. Excess risk of renal allograft loss associated with cigarette smoking. Transplantation. 2001;71(12):1752-7.
  • 312. KDIGO Anemia Work Group. KDIGO clinical practice guideline for anemia in chronic kidney disease. Kidney inter. 2012;2:279-335.
  • 313. McLean E, Cogswell M, Egli I, Wojdyla D, de Benoist B. Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993-2005. Public health nutrition. 2009;12(4):444-54.
  • 314. World Health Organization. Worldwide prevalence of anaemia 1993–2005: WHO global database on anaemia. 2008.
  • 315. Levin A, Djurdjev O, Thompson C, Barrett B, Ethier J, Carlisle E, et al. Canadian randomized trial of hemoglobin maintenance to prevent or delay left ventricular mass growth in patients with CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005;46(5):799-811.
  • 316. Pfeffer MA, Burdmann EA, Chen CY, Cooper ME, de Zeeuw D, Eckardt KU, et al. A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. The New England journal of medicine. 2009;361(21):2019-32.
  • 317. Roger SD, McMahon LP, Clarkson A, Disney A, Harris D, Hawley C, et al. Effects of early and late intervention with epoetin alpha on left ventricular mass among patients with chronic kidney disease (stage 3 or 4): results of a randomized clinical trial. J Am Soc Nephrol. 2004;15(1):148-56.
  • 318. KDIGO CKD-MBD Work Group. KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD). Kidney international Supplement. 2009;76:1-130.
  • 319. Levin A, Bakris GL, Molitch M, Smulders M, Tian J, Williams LA, et al. Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease. Kidney international. 2007;71(1):31-8.
  • 320. Moranne O, Froissart M, Rossert J, Gauci C, Boffa JJ, Haymann JP, et al. Timing of onset of CKD-related metabolic complications. J Am Soc Nephrol. 2009;20(1):164-71.
  • 321. Vassalotti JA, Uribarri J, Chen SC, Li S, Wang C, Collins AJ, et al. Trends in mineral metabolism: Kidney Early Evaluation Program (KEEP) and the National Health and Nutrition Examination Survey (NHANES) 1999-2004. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2008;51(4 Suppl 2):S56-68.
  • 322. Stevens LA, Djurdjev O, Cardew S, Cameron EC, Levin A. Calcium, phosphate, and parathyroid hormone levels in combination and as a function of dialysis duration predict mortality: evidence for the complexity of the association between mineral metabolism and outcomes. J Am Soc Nephrol. 2004;15(3):770-9.
  • 323. Gutierrez OM, Isakova T, Andress DL, Levin A, Wolf M. Prevalence and severity of disordered mineral metabolism in Blacks with chronic kidney disease. Kidney international. 2008;73(8):956-62.
  • 324. Gutierrez OM, Farwell WR, Kermah D, Taylor EN. Racial differences in the relationship between vitamin D, bone mineral density, and parathyroid hormone in the National Health and Nutrition Examination Survey. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2011;22(6):1745-53.
  • 325. Nickolas TL, Leonard MB, Shane E. Chronic kidney disease and bone fracture: a growing concern. Kidney international. 2008;74(6):721-31.
  • 326. Bacchetta J, Boutroy S, Vilayphiou N, Juillard L, Guebre-Egziabher F, Rognant N, et al. Early impairment of trabecular microarchitecture assessed with HR-pQCT in patients with stage II-IV chronic kidney disease. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2010;25(4):849-57.
  • 327. Nickolas TL, Stein E, Cohen A, Thomas V, Staron RB, McMahon DJ, et al. Bone mass and microarchitecture in CKD patients with fracture. J Am Soc Nephrol. 2010;21(8):1371-80.
  • 328. Nickolas TL, Cremers S, Zhang A, Thomas V, Stein E, Cohen A, et al. Discriminants of prevalent fractures in chronic kidney disease. J Am Soc Nephrol. 2011;22(8):1560-72.
  • 329. Palmer SC, Hayen A, Macaskill P, Pellegrini F, Craig JC, Elder GJ, et al. Serum levels of phosphorus, parathyroid hormone, and calcium and risks of death and cardiovascular disease in individuals with chronic kidney disease: a systematic review and meta-analysis. JAMA. 2011;305(11):1119-27.
  • 330. Adeney KL, Siscovick DS, Ix JH, Seliger SL, Shlipak MG, Jenny NS, et al. Association of serum phosphate with vascular and valvular calcification in moderate CKD. J Am Soc Nephrol. 2009;20(2):381-7.
  • 331. Moe SM, Zidehsarai MP, Chambers MA, Jackman LA, Radcliffe JS, Trevino LL, et al. Vegetarian compared with meat dietary protein source and phosphorus homeostasis in chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN. 2011;6(2):257-64.
  • 332. Sigrist MK, Chiarelli G, Lim L, Levin A. Early initiation of phosphate lowering dietary therapy in non-dialysis chronic kidney disease: a critical review. Journal of renal care. 2009;35 Suppl 1:71-8.
  • 333. Lynch KE, Lynch R, Curhan GC, Brunelli SM. Prescribed dietary phosphate restriction and survival among hemodialysis patients. Clinical journal of the American Society of Nephrology : CJASN. 2011;6(3):620-9.
  • 334. Navaneethan SD, Palmer SC, Vecchio M, Craig JC, Elder GJ, Strippoli GF. Phosphate binders for preventing and treating bone disease in chronic kidney disease patients. The Cochrane database of systematic reviews. 2011(2):CD006023.
  • 335. Mehrotra R, Kermah D, Budoff M, Salusky IB, Mao SS, Gao YL, et al. Hypovitaminosis D in chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN. 2008;3(4):1144-51.
  • 336. Navaneethan SD, Schold JD, Arrigain S, Jolly SE, Jain A, Schreiber MJ, Jr., et al. Low 25-hydroxyvitamin D levels and mortality in non-dialysis-dependent CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2011;58(4):536-43.
  • 337. Kandula P, Dobre M, Schold JD, Schreiber MJ, Jr., Mehrotra R, Navaneethan SD. Vitamin D supplementation in chronic kidney disease: a systematic review and metaanalysis of observational studies and randomized controlled trials. Clinical journal of the American Society of Nephrology : CJASN. 2011;6(1):50-62.
  • 338. Palmer SC, McGregor DO, Craig JC, Elder G, Macaskill P, Strippoli GF. Vitamin D compounds for people with chronic kidney disease requiring dialysis. The Cochrane database of systematic reviews. 2009(4):CD005633.
  • 339. Torregrosa JV, Ramos AM. [Use of bisphosphonates in chronic kidney disease]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia. 2010;30(3):288-96.
  • 340. Miller PD. The kidney and bisphosphonates. Bone. 2011;49(1):77-81.
  • 341. Bhan I, Dubey A, Wolf M. Diagnosis and management of mineral metabolism in CKD. Journal of general internal medicine. 2010;25(7):710-6.
  • 342. Courtney AE, Leonard N, McCloskey MC et al. Bisphosphonate prescribing in chronic kidney disease. J R Coll Physicians Edinb 2009; 39: 4–9.
  • 343. Ayus JC, Krothapalli RK. Effect of bicarbonate administration on cardiac function. The American journal of medicine. 1989;87(1):5-6.
  • 344. Bailey JL, Wang X, England BK, Price SR, Ding X, Mitch WE. The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway. The Journal of clinical investigation. 1996;97(6):1447-53.
  • 345. Domrongkitchaiporn S, Pongskul C, Sirikulchayanonta V, Stitchantrakul W, Leeprasert V, Ongphiphadhanakul B, et al. Bone histology and bone mineral density after correction of acidosis in distal renal tubular acidosis. Kidney international. 2002;62(6):2160- 6.
  • 346. Kovesdy CP, Anderson JE, Kalantar-Zadeh K. Association of serum bicarbonate levels with mortality in patients with non-dialysis-dependent CKD. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2009;24(4):1232-7.
  • 347. Mak RH. Effect of metabolic acidosis on insulin action and secretion in uremia. Kidney international. 1998;54(2):603-7.
  • 348. Menon V, Tighiouart H, Vaughn NS, Beck GJ, Kusek JW, Collins AJ, et al. Serum bicarbonate and long-term outcomes in CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2010;56(5):907-14.
  • 349. Mitch WE, Price SR. Mechanisms activated by kidney disease and the loss of muscle mass. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2001;38(6):1337-42.
  • 350. Navaneethan SD, Schold JD, Arrigain S, Jolly SE, Wehbe E, Raina R, et al. Serum bicarbonate and mortality in stage 3 and stage 4 chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN. 2011;6(10):2395-402.
  • 351. Raphael KL, Wei G, Baird BC, Greene T, Beddhu S. Higher serum bicarbonate levels within the normal range are associated with better survival and renal outcomes in African Americans. Kidney international. 2011;79(3):356-62.
  • 352. Shah SN, Abramowitz M, Hostetter TH, Melamed ML. Serum bicarbonate levels and the progression of kidney disease: a cohort study. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2009;54(2):270-7.
  • 353. Bright R. Reports of Medical Cases, Selected with a View of Illustrating the Symptoms and Cure of Diseases by a Reference to Morbid Anatomy Brown & Green ed. London1827.
  • 354. Osman AA. Originally published as Volume 2, Issue 5592THE VALUE OF ALKALIS IN THE TREATMENT OF CHRONIC NEPHRITIS. The Lancet. 1930;216(5592):945-9.
  • 355. Lyon DM, Dunlop DM, Stewart CP. The alkaline treatment of chronic nephritis. Lancet. 1931;2:1009–13.
  • 356. Rustom R, Grime JS, Costigan M, Maltby P, Hughes A, Taylor W, et al. Oral sodium bicarbonate reduces proximal renal tubular peptide catabolism, ammoniogenesis, and tubular damage in renal patients. Renal failure. 1998;20(2):371-82.
  • 357. Mathur RP, Dash SC, Gupta N, Prakash S, Saxena S, Bhowmik D. Effects of correction of metabolic acidosis on blood urea and bone metabolism in patients with mild to moderate chronic kidney disease: a prospective randomized single blind controlled trial. Renal failure. 2006;28(1):1-5.
  • 358. de Brito-Ashurst I, Varagunam M, Raftery MJ, Yaqoob MM. Bicarbonate supplementation slows progression of CKD and improves nutritional status. J Am Soc Nephrol. 2009;20(9):2075-84.
  • 359. Phisitkul S, Khanna A, Simoni J, Broglio K, Sheather S, Rajab MH, et al. Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR. Kidney international. 2010;77(7):617-23.
  • 360. Husted FC, Nolph KD, Maher JF. NaHCO3 and NaCl tolerance in chronic renal failure. J Clin Invest 1975;56:414-9.
  • 361. Husted FC, Nolph KD. NaHCO3 and NaCl tolerance in chronic renal failure II. Clinical nephrology. 1977;7(1):21-5.
  • 362. Hallan SI, Dahl K, Oien CM, Grootendorst DC, Aasberg A, Holmen J, et al. Screening strategies for chronic kidney disease in the general population: follow-up of cross sectional health survey. Bmj. 2006;333(7577):1047.
  • 363. McCullough PA, Li S, Jurkovitz CT, Stevens L, Collins AJ, Chen SC, et al. Chronic kidney disease, prevalence of premature cardiovascular disease, and relationship to shortterm mortality. American heart journal. 2008;156(2):277-83.
  • 364. Wright RS, Reeder Gs Fau – Herzog CA, Herzog Ca Fau – Albright RC, Albright Rc Fau – Williams BA, Williams Ba Fau – Dvorak DL, Dvorak Dl Fau – Miller WL, et al. Acute myocardial infarction and renal dysfunction: a high-risk combination. Annals of internal medicine. 2002;137(1539-3704 (Electronic)):563-70.
  • 365. Shlipak MG, Heidenreich PA, Noguchi H, Chertow GM, Browner WS, McClellan MB. Association of renal insufficiency with treatment and outcomes after myocardial infarction in elderly patients. Annals of internal medicine. 2002;137(7):555-62.
  • 366. Anavekar NS, McMurray Jj Fau – Velazquez EJ, Velazquez Ej Fau – Solomon SD, Solomon Sd Fau – Kober L, Kober L Fau – Rouleau J-L, Rouleau Jl Fau – White HD, et al. Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction. The New England journal of medicine. 2004;351:1285-95.
  • 367. Sarnak MJ. Cardiovascular complications in chronic kidney disease. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2003;41(5 Suppl):11-7.
  • 368. Hemmelgarn BR, Manns Bj Fau – Lloyd A, Lloyd A Fau – James MT, James Mt Fau – Klarenbach S, Klarenbach S Fau – Quinn RR, Quinn Rr Fau – Wiebe N, et al. Relation between kidney function, proteinuria, and adverse outcomes. JAMA. 2010;303:423-9.
  • 369. Gerstein HC, Mann Jf Fau – Yi Q, Yi Q Fau – Zinman B, Zinman B Fau – Dinneen SF, Dinneen Sf Fau – Hoogwerf B, Hoogwerf B Fau – Halle JP, et al. Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. JAMA. 2001;286:421-6
  • 370. Hallan S, Astor B, Romundstad S, Aasarod K, Kvenild K, Coresh J. Association of kidney function and albuminuria with cardiovascular mortality in older vs younger individuals: The HUNT II Study. Archives of internal medicine. 2007;167(22):2490-6.
  • 371. Ibsen H, Wachtell K, Olsen MH, Borch-Johnsen K, Lindholm LH, Mogensen CE, et al. Albuminuria and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE Study. Kidney international Supplement. 2004(92):S56-8.
  • 372. Menon V, Shlipak Mg Fau – Wang X, Wang X Fau – Coresh J, Coresh J Fau – Greene T, Greene T Fau – Stevens L, Stevens L Fau – Kusek JW, et al. Cystatin C as a risk factor for outcomes in chronic kidney disease. Annals of internal medicine. 2007;147:19-27.
  • 373. Peralta CA, Katz R Fau – Sarnak MJ, Sarnak Mj Fau – Ix J, Ix J Fau – Fried LF, Fried Lf Fau – De Boer I, De Boer I Fau – Palmas W, et al. Cystatin C identifies chronic kidney disease patients at higher risk for complications. J Am Soc Nephrol. 2011;22:147-55.
  • 374. Strippoli GF, Tognoni G, Navaneethan SD, Nicolucci A, Craig JC. Haemoglobin targets: we were wrong, time to move on. Lancet. 2007;369(9559):346-50.
  • 375. Phrommintikul A, Haas SJ, Elsik M, Krum H. Mortality and target haemoglobin concentrations in anaemic patients with chronic kidney disease treated with erythropoietin: a meta-analysis. Lancet. 2007;369(9559):381-8.
  • 376. Eckardt KU, Scherhag A, Macdougall IC, Tsakiris D, Clyne N, Locatelli F, et al. Left ventricular geometry predicts cardiovascular outcomes associated with anemia correction in CKD. J Am Soc Nephrol. 2009;20(12):2651-60.
  • 377. Kestenbaum B, Sampson Jn Fau – Rudser KD, Rudser Kd Fau – Patterson DJ, Patterson Dj Fau – Seliger SL, Seliger Sl Fau – Young B, Young B Fau – Sherrard DJ, et al. Serum phosphate levels and mortality risk among people with chronic kidney disease. J Am Soc Nephrol . 2005;16:520–8.
  • 378. Halimi JM, Giraudeau B, Vol S, Caces E, Nivet H, Lebranchu Y, et al. Effects of current smoking and smoking discontinuation on renal function and proteinuria in the general population. Kidney international. 2000;58(3):1285-92.
  • 379. Boyce ML, Robergs RA, Avasthi PS, Roldan C, Foster A, Montner P, et al. Exercise training by individuals with predialysis renal failure: cardiorespiratory endurance, hypertension, and renal function. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1997;30(2):180-92.
  • 380. Baigent C, Landray MJ, Reith C, Emberson J, Wheeler DC, Tomson C, et al. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. Lancet. 2011;377(9784):2181-92.
  • 381. Tonelli M, Wanner C, Kidney Disease: Improving Global Outcomes Lipid Guideline Development Work Group M. Lipid management in chronic kidney disease: synopsis of the Kidney Disease: Improving Global Outcomes 2013 clinical practice guideline. Annals of internal medicine. 2014;160(3):182.
  • 382. Jardine MJ, Ninomiya T, Perkovic V, Cass A, Turnbull F, Gallagher MP, et al. Aspirin Is Beneficial in Hypertensive Patients With Chronic Kidney Disease: A Post-Hoc Subgroup Analysis of a Randomized Controlled Trial. Journal of the American College of Cardiology. 2010;56(12):956-65.
  • 383. Angiolillo DJ, Bernardo E, Capodanno D, Vivas D, Sabate M, Ferreiro JL, et al. Impact of chronic kidney disease on platelet function profiles in diabetes mellitus patients with coronary artery disease taking dual antiplatelet therapy. Journal of the American College of Cardiology. 2010;55(11):1139-46.
  • 384. Best PJM, Steinhubl SR, Berger PB, Dasgupta A, Brennan DM, Szczech LA, et al. The efficacy and safety of short- and long-term dual antiplatelet therapy in patients with mild or moderate chronic kidney disease: Results from the Clopidogrel for the Reduction of Events During Observation (CREDO) Trial. American heart journal. 2008;155(4):687-93.
  • 385. Di Angelantonio E, Chowdhury R, Sarwar N, Aspelund T, Danesh J, Gudnason V. Chronic kidney disease and risk of major cardiovascular disease and non-vascular mortality: prospective population based cohort study. Bmj. 2010;341:c4986.
  • 386. Parikh NI, Hwang Sj Fau – Larson MG, Larson Mg Fau – Levy D, Levy D Fau – Fox CS, Fox CS. Chronic kidney disease as a predictor of cardiovascular disease (from the Framingham Heart Study). The American journal of cardiology. 2008;102(0002-9149 (Print)):47-53.
  • 387. McAlister FA, Ezekowitz J, Tonelli M, Armstrong PW. Renal insufficiency and heart failure: prognostic and therapeutic implications from a prospective cohort study. Circulation. 2004;109(8):1004-9.
  • 388. Smith GL, Lichtman JH, Bracken MB, Shlipak MG, Phillips CO, DiCapua P, et al. Renal impairment and outcomes in heart failure: systematic review and meta-analysis. Journal of the American College of Cardiology. 2006;47(10):1987-96.
  • 389. Hillege HL, Nitsch D Fau – Pfeffer MA, Pfeffer Ma Fau – Swedberg K, Swedberg K Fau – McMurray JJV, McMurray Jj Fau – Yusuf S, Yusuf S Fau – Granger CB, et al. Renal function as a predictor of outcome in a broad spectrum of patients with heart failure. Circulation. 2006;113:671-8.
  • 390. Shlipak MG, Smith GL, Rathore SS, Massie BM, Krumholz HM. Renal function, digoxin therapy, and heart failure outcomes: evidence from the digoxin intervention group trial. J Am Soc Nephrol. 2004;15(8):2195-203.
  • 391. Smith GL, Shlipak MG, Havranek EP, Masoudi FA, McClellan WM, Foody JM, et al. Race and renal impairment in heart failure: mortality in blacks versus whites. Circulation. 2005;111(10):1270-7.
  • 392. Anand IS, Bishu K, Rector TS, Ishani A, Kuskowski MA, Cohn JN. Proteinuria, chronic kidney disease, and the effect of an angiotensin receptor blocker in addition to an angiotensin-converting enzyme inhibitor in patients with moderate to severe heart failure. Circulation. 2009;120(16):1577-84.
  • 393. Ezekowitz J, McAlister FA, Humphries KH, Norris CM, Tonelli M, Ghali WA, et al. The association among renal insufficiency, pharmacotherapy, and outcomes in 6,427 patients with heart failure and coronary artery disease. Journal of the American College of Cardiology. 2004;44(8):1587-92.
  • 394. Gottlieb SS, Abraham W, Butler J, Forman DE, Loh E, Massie BM, et al. The prognostic importance of different definitions of worsening renal function in congestive heart failure. Journal of cardiac failure. 2002;8(3):136-41.
  • 395. Middleton RJ, Parfrey PS, Foley RN. Left ventricular hypertrophy in the renal patient. J Am Soc Nephrol. 2001;12(5):1079-84.
  • 396. Levin A, Singer J, Thompson CR, Ross H, Lewis M. Prevalent left ventricular hypertrophy in the predialysis population: identifying opportunities for intervention. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1996;27(3):347-54.
  • 397. Ha SK, Park HS, Kim SJ, Park CH, Kim DS, Kim HS. Prevalence and patterns of left ventricular hypertrophy in patients with predialysis chronic renal failure. Journal of Korean medical science. 1998;13(5):488-94.
  • 398. Parfrey PS, Foley RN, Harnett JD, Kent GM, Murray DC, Barre PE. Outcome and risk factors for left ventricular disorders in chronic uraemia. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 1996;11(7):1277-85.
  • 399. Cerasola G, Nardi E, Palermo A, Mule G, Cottone S. Epidemiology and pathophysiology of left ventricular abnormalities in chronic kidney disease: a review. Journal of nephrology. 2011;24(1):1-10.
  • 400. Ahmed A, Rich MW, Sanders PW, Perry GJ, Bakris GL, Zile MR, et al. Chronic kidney disease associated mortality in diastolic versus systolic heart failure: a propensity matched study. The American journal of cardiology. 2007;99(3):393-8.
  • 401. Lazzeri C, Valente S, Tarquini R, Gensini GF. Cardiorenal syndrome caused by heart failure with preserved ejection fraction. International journal of nephrology. 2011;2011:634903.
  • 402. Levin A, Thompson CR, Ethier J, Carlisle EJ, Tobe S, Mendelssohn D, et al. Left ventricular mass index increase in early renal disease: impact of decline in hemoglobin. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1999;34(1):125-34.
  • 403. Go AS, Yang J, Ackerson LM, Lepper K, Robbins S, Massie BM, et al. Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: the Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study. Circulation. 2006;113(23):2713-23.
  • 404. Shlipak MG, Katz R, Kestenbaum B, Fried LF, Siscovick D, Sarnak MJ. Clinical and subclinical cardiovascular disease and kidney function decline in the elderly. Atherosclerosis. 2009;204(1):298-303.
  • 405. Balamuthusamy S, Srinivasan L, Verma M, Adigopula S, Jalandhara N, Hathiwala S, et al. Renin angiotensin system blockade and cardiovascular outcomes in patients with chronic kidney disease and proteinuria: a meta-analysis. American heart journal. 2008;155(5):791-805.
  • 406. Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. The New England journal of medicine. 2001;345(12):851-60.
  • 407. Erdmann E, Lechat P, Verkenne P, Wiemann H. Results from post-hoc analyses of the CIBIS II trial: effect of bisoprolol in high-risk patient groups with chronic heart failure. European journal of heart failure. 2001;3(4):469-79.
  • 408. Wali RK, Iyengar M, Beck GJ, Chartyan DM, Chonchol M, Lukas MA, et al. Efficacy and safety of carvedilol in treatment of heart failure with chronic kidney disease: a metaanalysis of randomized trials. Circulation Heart failure. 2011;4(1):18-26.
  • 409. Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. The New England journal of medicine. 1999;341(10):709-17.
  • 410. Juurlink DN, Mamdani MM, Lee DS, Kopp A, Austin PC, Laupacis A, et al. Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. The New England journal of medicine. 2004;351(6):543-51.
  • 411. Abdel-Qadir HM, Chugh S, Lee DS. Improving prognosis estimation in patients with heart failure and the cardiorenal syndrome. International journal of nephrology. 2011;2011:351672.
  • 412. Levin ER, Gardner DG, Samson WK. Natriuretic peptides. The New England journal of medicine. 1998;339(5):321-8.
  • 413. Wiley CL, Switzer SP, Berg RL, Glurich I, Dart RA. Association of B-type natriuretic Peptide levels with estimated glomerular filtration rate and congestive heart failure. Clinical medicine & research. 2010;8(1):7-12.
  • 414. Madsen LH, Ladefoged S, Corell P, Schou M, Hildebrandt PR, Atar D. N-terminal pro brain natriuretic peptide predicts mortality in patients with end-stage renal disease in hemodialysis. Kidney international. 2007;71(6):548-54.
  • 415. Gustafsson F, Steensgaard-Hansen F, Badskjaer J, Poulsen AH, Corell P, Hildebrandt P. Diagnostic and prognostic performance of N-terminal ProBNP in primary care patients with suspected heart failure. Journal of cardiac failure. 2005;11(5 Suppl):S15-20.
  • 416. McCullough PA, Omland T, Maisel AS. B-type natriuretic peptides: a diagnostic breakthrough for clinicians. Reviews in cardiovascular medicine. 2003;4(2):72-80.
  • 417. Maisel A, Mehra MR. Understanding B-type natriuretic peptide and its role in diagnosing and monitoring congestive heart failure. Clin Cornerstone 2005;7:S7-17.
  • 418. Wright SP, Doughty RN, Pearl A, Gamble GD, Whalley GA, Walsh HJ, et al. Plasma amino-terminal pro-brain natriuretic peptide and accuracy of heart-failure diagnosis in primary care: a randomized, controlled trial. Journal of the American College of Cardiology. 2003;42(10):1793-800.
  • 419. Yamamoto K, Burnett JC, Jougasaki M, Nishimura RA, Bailey KR, Saito Y, et al. Superiority of Brain Natriuretic Peptide as a Hormonal Marker of Ventricular Systolic and Diastolic Dysfunction and Ventricular Hypertrophy. Hypertension. 1996;28(6):988-94.
  • 420. Burnett JC, Jr., Kao PC, Hu DC, Heser DW, Heublein D, Granger JP, et al. Atrial natriuretic peptide elevation in congestive heart failure in the human. Science. 1986;231(4742):1145-7.
  • 421. Mueller C, Laule-Kilian K, Scholer A, Nusbaumer C, Zeller T, Staub D, et al. B-type natriuretic peptide for acute dyspnea in patients with kidney disease: insights from a randomized comparison. Kidney international. 2005;67(1):278-84.
  • 422. Vickery S, Price CP, John RI, Abbas NA, Webb MC, Kempson ME, et al. B-type natriuretic peptide (BNP) and amino-terminal proBNP in patients with CKD: relationship to renal function and left ventricular hypertrophy. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005;46(4):610-20.
  • 423. Ishibe S, Peixoto AJ. Methods of assessment of volume status and intercompartmental fluid shifts in hemodialysis patients: implications in clinical practice. Seminars in dialysis. 2004;17(1):37-43.
  • 424. Tagore R, Ling LH, Yang H, Daw HY, Chan YH, Sethi SK. Natriuretic peptides in chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN. 2008;3(6):1644-51.
  • 425. Takami Y, Horio T, Iwashima Y, Takiuchi S, Kamide K, Yoshihara F, et al. Diagnostic and prognostic value of plasma brain natriuretic peptide in non-dialysis-dependent CRF. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2004;44(3):420-8.
  • 426. Zoccali C, Mallamaci F, Benedetto FA, Tripepi G, Parlongo S, Cataliotti A, et al. Cardiac natriuretic peptides are related to left ventricular mass and function and predict mortality in dialysis patients. J Am Soc Nephrol. 2001;12(7):1508-15.
  • 427. Suresh M, Farrington K. Natriuretic peptides and the dialysis patient. Seminars in dialysis. 2005;18(5):409-19.
  • 428. Kistorp C, Raymond I, Pedersen F, Gustafsson F, Faber J, Hildebrandt P. N-terminal pro-brain natriuretic peptide, C-reactive protein, and urinary albumin levels as predictors of mortality and cardiovascular events in older adults. JAMA. 2005;293(13):1609-16.
  • 429. Bettencourt P, Azevedo A, Pimenta J, Frioes F, Ferreira S, Ferreira A. N-terminalpro-brain natriuretic peptide predicts outcome after hospital discharge in heart failure patients. Circulation. 2004;110(15):2168-74.
  • 430. Gardner RS, Ozalp F, Murday AJ, Robb SD, McDonagh TA. N-terminal pro-brain natriuretic peptide. A new gold standard in predicting mortality in patients with advanced heart failure. European heart journal. 2003;24(19):1735-43.
  • 431. Kragelund CB, Gronning BA, Kober L, Hildebrandt PR, Steffensen R. [Prognostic value of N-terminal pro-BNP-type natriuretic peptide in patients with stable coronary heart disease–secondary publication]. Ugeskrift for laeger. 2006;168(7):697-700.
  • 432. Omland T, Persson A, Ng L, O’Brien R, Karlsson T, Herlitz J, et al. N-terminal pro-Btype natriuretic peptide and long-term mortality in acute coronary syndromes. Circulation. 2002;106(23):2913-8.
  • 433. Olsen MH, Wachtell K, Tuxen C, Fossum E, Bang LE, Hall C, et al. N-terminal probrain natriuretic peptide predicts cardiovascular events in patients with hypertension and left ventricular hypertrophy: a LIFE study. Journal of hypertension. 2004;22(8):1597-604.
  • 434. Barret BJ, Culleton B, Bruce. Reducing the burden of cardiovascular disease in Patients on dialysis. Van Nuys, CA, ETATS-UNIS: Creative Age Publications; 2002. 7 p.
  • 435. Beciani M, Tedesco A, Violante A, Cipriani S, Azzarito M, Sturniolo A, et al. Cardiac troponin I (2nd generation assay) in chronic haemodialysis patients: prevalence and prognostic value. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2003;18(5):942-6.
  • 436. Apple FS, Wu AH. Myocardial infarction redefined: role of cardiac troponin testing. Clinical chemistry. 2001;47(3):377-9.
  • 437. McLaurin MD, Apple Fs Fau – Voss EM, Voss Em Fau – Herzog CA, Herzog Ca Fau – Sharkey SW, Sharkey SW. Cardiac troponin I, cardiac troponin T, and creatine kinase MB in dialysis patients without ischemic heart disease: evidence of cardiac troponin T expression in skeletal muscle. Clinical chemistry. 1997;43(0009-9147 (Print)):976–82.
  • 438. Musso P, Cox I, Vidano E, Zambon D, Panteghini M. Cardiac troponin elevations in chronic renal failure: prevalence and clinical significance. Clinical biochemistry. 1999;32(2):125-30.
  • 439. Alpert Js Fau – Thygesen K, Thygesen K Fau – Antman E, Antman E Fau – Bassand JP, Bassand JP. Myocardial infarction redefined–a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. Journal of the American College of Cardiology. 2000;36(0735-1097 (Print)):959-69.
  • 440. Collinson PO, Boa FG, Gaze DC. Measurement of cardiac troponins. Annals of clinical biochemistry. 2001;38(Pt 5):423-49.
  • . Lindahl B, Venge P, Wallentin L. Troponin T identifies patients with unstable coronary artery disease who benefit from long-term antithrombotic protection. Fragmin in Unstable Coronary Artery Disease (FRISC) Study Group. Journal of the American College of Cardiology. 1997;29(1):43-8.
  • 442. Rabbani LE. Acute coronary syndromes–beyond myocyte necrosis. The New England journal of medicine. 2001;345(14):1057-9.
  • 443. Tun A, Khan IA, Win MT, Hussain A, Hla TA, Wattanasuwan N, et al. Specificity of cardiac troponin I and creatine kinase-MB isoenzyme in asymptomatic long-term hemodialysis patients and effect of hemodialysis on these cardiac markers. Cardiology. 1998;90(4):280-5.
  • 444. Wood GN, Keevil B, Gupta J, Foley R, Bubtana A, McDowell G, et al. Serum troponin T measurement in patients with chronic renal impairment predicts survival and vascular disease: a 2 year prospective study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2003;18(8):1610-5.
  • 445. Abbas NA, John RI, Webb MC, Kempson ME, Potter AN, Price CP, et al. Cardiac troponins and renal function in nondialysis patients with chronic kidney disease. Clinical chemistry. 2005;51(11):2059-66.
  • 446. Kinnunen P, Vuolteenaho O, Ruskoaho H. Mechanisms of atrial and brain natriuretic peptide release from rat ventricular myocardium: effect of stretching. Endocrinology. 1993;132(5):1961-70.
  • 447. deFilippi C, Wasserman S, Rosanio S, Tiblier E, Sperger H, Tocchi M, et al. Cardiac troponin T and C-reactive protein for predicting prognosis, coronary atherosclerosis, and cardiomyopathy in patients undergoing long-term hemodialysis. JAMA. 2003;290(3):353-9.
  • 448. Hayashi T, Obi Y, Kimura T, Iio K, Sumitsuji S, Takeda Y, et al. Cardiac troponin T predicts occult coronary artery stenosis in patients with chronic kidney disease at the start of renal replacement therapy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2008;23(9):2936-42.
  • 449. Roongsritong C, Warraich I, Bradley C. Common causes of troponin elevations in the absence of acute myocardial infarction: incidence and clinical significance. Chest. 2004;125(5):1877-84.
  • 450. Apple FS, Murakami MM, Pearce LA, Herzog CA. Multi-biomarker risk stratification of N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and cardiac troponin T and I in end-stage renal disease for all-cause death. Clinical chemistry. 2004;50(12):2279-85.
  • 451. De Zoysa JR. Cardiac troponins and renal disease. Nephrology. 2004;9(2):83-8.
  • 452. Deegan PB, Lafferty ME, Blumsohn A, Henderson IS, McGregor E. Prognostic value of troponin T in hemodialysis patients is independent of comorbidity. Kidney international. 2001;60(6):2399-405.
  • 453. Dierkes J, Domrose U, Westphal S, Ambrosch A, Bosselmann HP, Neumann KH, et al. Cardiac troponin T predicts mortality in patients with end-stage renal disease. Circulation. 2000;102(16):1964-9.
  • 454. Fehr T, Knoflach A Fau – Ammann P, Ammann P Fau – Pei P, Pei P Fau – Binswanger U, Binswanger U. Differential use of cardiac troponin T versus I in hemodialysis patients. Clinical nephrology. 2003;59:35-9.
  • 455. Francis GS, Tang WH. Cardiac troponins in renal insufficiency and other nonischemic cardiac conditions. Progress in cardiovascular diseases. 2004;47(3):196-206.
  • 456. Freda BJ, Tang WH, Van Lente F, Peacock WF, Francis GS. Cardiac troponins in renal insufficiency: review and clinical implications. Journal of the American College of Cardiology. 2002;40(12):2065-71.
  • 457. Lamb EJ, Webb MC, Abbas NA. The significance of serum troponin T in patients with kidney disease: a review of the literature. Annals of clinical biochemistry. 2004;41(Pt 1):1-9.
  • 458. Lowbeer C, Ottosson-Seeberger A, Gustafsson SA, Norrman R, Hulting J, Gutierrez A. Increased cardiac troponin T and endothelin-1 concentrations in dialysis patients may indicate heart disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 1999;14(8):1948-55.
  • 459. Needham DM, Shufelt KA, Tomlinson G, Scholey JW, Newton GE. Troponin I and T levels in renal failure patients without acute coronary syndrome: a systematic review of the literature. The Canadian journal of cardiology. 2004;20(12):1212-8.
  • 460. Ooi DS, Zimmerman D, Graham J, Wells GA. Cardiac Troponin T Predicts LongTerm Outcomes in Hemodialysis Patients. Clinical chemistry. 2001;47(3):412-7.
  • 461. Roberts MA, Fernando D, Macmillan N, Proimos G, Bach LA, Power DA, et al. Single and serial measurements of cardiac troponin I in asymptomatic patients on chronic hemodialysis. Clinical nephrology. 2004;61(1):40-6.
  • 462. Iliou MC, Fumeron C, Benoit MO, Tuppin P, Courvoisier CL, Calonge VM, et al. Factors associated with increased serum levels of cardiac troponins T and I in chronic haemodialysis patients: Chronic Haemodialysis And New Cardiac Markers Evaluation (CHANCE) study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2001;16(7):1452-8.
  • 463. Collinson PO, Hadcocks L, Foo Y, Rosalki SB, Stubbs PJ, Morgan SH, et al. Cardiac troponins in patients with renal dysfunction. Annals of clinical biochemistry. 1998;35 ( Pt 3):380-6.
  • 464. Roppolo LP, Fitzgerald R, Dillow J, Ziegler T, Rice M, Maisel A. A comparison of troponin T and troponin I as predictors of cardiac events in patients undergoing chronic dialysis at a Veteran’s Hospital: a pilot study. Journal of the American College of Cardiology. 1999;34(2):448-54.
  • 465. Mallamaci F, Zoccali C, Parlongo S, Tripepi G, Benedetto FA, Cutrupi S, et al. Troponin is related to left ventricular mass and predicts all-cause and cardiovascular mortality in hemodialysis patients. American Journal of Kidney Diseases. 2002;40(1):68-75.
  • 466. de Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA. 2010;304(22):2503-12.
  • 467. Haller C, Zehelein J, Remppis A, Muller-Bardorff M, Katus HA. Cardiac troponin T in patients with end-stage renal disease: absence of expression in truncal skeletal muscle. Clinical chemistry. 1998;44(5):930-8.
  • 468. Abaci A, Ekici E, Oguzhan A, Tokgoz B, Utas C. Cardiac troponins T and I in patients with end-stage renal disease: the relation with left ventricular mass and their prognostic value. Clinical cardiology. 2004;27(12):704-9.
  • 469. Ooi DS, House AA. Cardiac troponin T in hemodialyzed patients. Clinical chemistry. 1998;44(7):1410-6.
  • 470. Parfrey PS, Foley RN. The clinical epidemiology of cardiac disease in chronic renal failure. J Am Soc Nephrol. 1999;10(7):1606-15.
  • 471. McIntyre CW, Odudu A, Eldehni MT. Cardiac assessment in chronic kidney disease. Current opinion in nephrology and hypertension. 2009;18(6):501-6.
  • 472. Lentine KL, Hurst FP, Jindal RM. Cardiovascular risk assessment among potential kidney transplant candidates: approaches and controversies. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2010;55:152-67.
  • 473. Bennett WM, Kloster F, Rosch J, Barry J, Porter GA. Natural history of asymptomatic coronary arteriographic lesions in diabetic patients with end-stage renal disease. The American journal of medicine. 1978;65(5):779-84.
  • 474. Braun WE, Phillips DF, Vidt DG, Novick AC, Nakamoto S, Popowniak KL, et al. Coronary artery disease in 100 diabetics with end-stage renal failure. Transplantation proceedings. 1984;16(3):603-7.
  • 475. Lorber MI, Van Buren CT, Flechner SM, Cameron L, Leatherwood J, Walker WE, et al. Pretransplant coronary arteriography for diabetic renal transplant recipients. Transplantation proceedings. 1987;19(1 Pt 2):1539-41.
  • 476. Manske CL, Wilson RF, Wang Y, Thomas W. Prevalence of, and risk factors for, angiographically determined coronary artery disease in type I-diabetic patients with nephropathy. Archives of internal medicine. 1992;152(12):2450-5.
  • 477. Weinrauch L, D’Elia JA, Healy RW, Gleason RE, Christleib AR, Leland OS, Jr. Asymptomatic coronary artery disease: angiographic assessment of diabetics evaluated for renal transplantation. Circulation. 1978;58(6):1184-90.
  • 478. Dahan M, Viron BM, Faraggi M, Himbert DL, Lagallicier BJ, Kolta AM, et al. Diagnostic accuracy and prognostic value of combined dipyridamole-exercise thallium imaging in hemodialysis patients. Kidney international. 1998;54(1):255-62
  • 479. Koistinen MJ, Huikuri HV, Pirttiaho H, Linnaluoto MK, Takkunen JT. Evaluation of exercise electrocardiography and thallium tomographic imaging in detecting asymptomatic coronary artery disease in diabetic patients. British heart journal. 1990;63(1):7-11.
  • 480. Marwick TH, Steinmuller DR, Underwood DA, Hobbs RE, Go RT, Swift C, et al. Ineffectiveness of dipyridamole SPECT thallium imaging as a screening technique for coronary artery disease in patients with end-stage renal failure. Transplantation. 1990;49(1):100-3.
  • 481. Schmidt A, Stefenelli T, Schuster E, Mayer G. Informational contribution of noninvasive screening tests for coronary artery disease in patients on chronic renal replacement therapy. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2001;37(1):56-63.
  • 482. Morrow CE, Schwartz JS, Sutherland DE, Simmons RL, Ferguson RM, Kjellstrand CM, et al. Predictive value of thallium stress testing for coronary and cardiovascular events in uremic diabetic patients before renal transplantation. American journal of surgery. 1983;146(3):331-5.
  • 483. Patel AD, Abo-Auda WS, Davis JM, Zoghbi GJ, Deierhoi MH, Heo J, et al. Prognostic value of myocardial perfusion imaging in predicting outcome after renal transplantation. The American journal of cardiology. 2003;92(2):146-51.
  • 484. Rabbat CG, Treleaven DJ, Russell JD, Ludwin D, Cook DJ. Prognostic value of myocardial perfusion studies in patients with end-stage renal disease assessed for kidney or kidney-pancreas transplantation: a meta-analysis. J Am Soc Nephrol. 2003;14(2):431-9.
  • 485. Wong CF, Little MA, Vinjamuri S, Hammad A, Harper JM. Technetium myocardial perfusion scanning in prerenal transplant evaluation in the United kingdom. Transplantation proceedings. 2008;40(5):1324-8.
  • 486. De Lima JJG, Sabbaga E, Vieira MLC, de Paula FJ, Ianhez LE, Krieger EM, et al. Coronary Angiography Is the Best Predictor of Events in Renal Transplant Candidates Compared With Noninvasive Testing. Hypertension. 2003;42(3):263-8.
  • . Hatta T, Nishimura S, Nishimura T. Prognostic risk stratification of myocardial ischaemia evaluated by gated myocardial perfusion SPECT in patients with chronic kidney disease. European journal of nuclear medicine and molecular imaging. 2009;36(11):1835- 41.
  • 488. Kusuoka H, Nishimura S, Yamashina A, Nakajima K, Nishimura T. Surveillance study for creating the national clinical database related to ECG-gated myocardial perfusion SPECT of ischemic heart disease: J-ACCESS study design. Annals of nuclear medicine. 2006;20(3):195-202.
  • 489. Momose M, Babazono T, Kondo C, Kobayashi H, Nakajima T, Kusakabe K. Prognostic significance of stress myocardial ECG-gated perfusion imaging in asymptomatic patients with diabetic chronic kidney disease on initiation of haemodialysis. European journal of nuclear medicine and molecular imaging. 2009;36(8):1315-21.
  • 490. Nakajima K, Nishimura T. Inter-institution preference-based variability of ejection fraction and volumes using quantitative gated SPECT with 99mTc-tetrofosmin: a multicentre study involving 106 hospitals. European journal of nuclear medicine and molecular imaging. 2006;33(2):127-33.
  • 491. Nekolla SG, Reder S, Saraste A, Higuchi T, Dzewas G, Preissel A, et al. Evaluation of the novel myocardial perfusion positron-emission tomography tracer 18F-BMS-747158- 02: comparison to 13N-ammonia and validation with microspheres in a pig model. Circulation. 2009;119(17):2333-42.
  • 492. Biomarkers Definitions Working G. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clinical pharmacology and therapeutics. 2001;69(3):89-95.
  • 493. Ix JH, Criqui MH. Epidemiology and diagnosis of peripheral arterial disease in patients with chronic kidney disease. Advances in chronic kidney disease. 2008;15(4):378- 83.
  • 494. Lau JF, Weinberg MD, Olin JW. Peripheral artery disease. Part 1: clinical evaluation and noninvasive diagnosis. Nature reviews Cardiology. 2011;8(7):405-18.
  • 495. O’Hare AM, Vittinghoff E, Hsia J, Shlipak MG. Renal insufficiency and the risk of lower extremity peripheral arterial disease: results from the Heart and Estrogen/Progestin Replacement Study (HERS). J Am Soc Nephrol. 2004;15(4):1046-51.
  • 496. O’Hare AM, Newman AB, Katz R, Fried LF, Stehman-Breen CO, Seliger SL, et al. Cystatin C and incident peripheral arterial disease events in the elderly: results from the Cardiovascular Health Study. Archives of internal medicine. 2005;165(22):2666-70.
  • 497. O’Hare AM, Glidden DV, Fox CS, Hsu CY. High prevalence of peripheral arterial disease in persons with renal insufficiency: results from the National Health and Nutrition Examination Survey 1999-2000. Circulation. 2004;109(3):320-3.
  • 498. Liew YP, Bartholomew JR, Demirjian S, Michaels J, Schreiber MJ, Jr. Combined effect of chronic kidney disease and peripheral arterial disease on all-cause mortality in a high-risk population. Clinical journal of the American Society of Nephrology : CJASN. 2008;3(4):1084-9.
  • 499. Lash JP, Go AS, Appel LJ, He J, Ojo A, Rahman M, et al. Chronic Renal Insufficiency Cohort (CRIC) Study: baseline characteristics and associations with kidney function. Clinical journal of the American Society of Nephrology : CJASN. 2009;4(8):1302-11.
  • 500. de Vinuesa SG, Ortega M, Martinez P, Goicoechea M, Campdera FG, Luno J. Subclinical peripheral arterial disease in patients with chronic kidney disease: prevalence and related risk factors. Kidney international Supplement. 2005(93):S44-7.
  • 501. Bello AK, Hemmelgarn B, Lloyd A, James MT, Manns BJ, Klarenbach S, et al. Associations among Estimated Glomerular Filtration Rate, Proteinuria, and Adverse Cardiovascular Outcomes. Clinical journal of the American Society of Nephrology : CJASN. 2011;6(6):1418-26.
  • 502. Wattanakit K, Folsom AR, Criqui MH, Kramer HJ, Cushman M, Shea S, et al. Albuminuria and peripheral arterial disease: Results from the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2008;201(1):212-6.
  • 503. Margolis DJ, Hofstad O, Feldman HI. Association Between Renal Failure and Foot Ulcer or Lower-Extremity Amputation in Patients With Diabetes. Diabetes Care. 2008;31(7):1331-6.
  • 504. Fuster V, Rydén LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation): Developed in Collaboration With the European Heart Rhythm Association and the Heart Rhythm Society. Circulation. 2006;114(7):e257-e354.
  • 505. Abbas AE, Goodman LM, Timmis R, Boura J. Predictors of poor outcome in female patients undergoing endovascular intervention. Journal of interventional cardiology. 2010;23(4):401-10.
  • 506. O’Hare AM, Bertenthal D, Sidawy AN, Shlipak MG, Sen S, Chren M-M. Renal Insufficiency and Use of Revascularization among a National Cohort of Men with Advanced Lower Extremity Peripheral Arterial Disease. Clinical Journal of the American Society of Nephrology. 2006;1(2):297-304.
  • 507. Sahni V, Choudhury D, Ahmed Z. Chemotherapy-associated renal dysfunction. Nature reviews Nephrology. 2009;5(8):450-62.
  • 508. Goodman and Gilman’s Pharmacological Basis of Therapeutics. 12th ed. New York: Brunston, L.L. Chabner, B.A. Knollman, B.A.; 2011.
  • 509. Martindale: The Complete Drug Reference. 37 th ed. Sweetman SC: Royal Pharmaceutical Society, London; 2011.
  • 510. Gokmen MR, Lord GM. Aristolochic acid nephropathy. Bmj. 2012;344:e4000.
  • 511. Su T, Zhang L, Li X, Zuo L, Zhang P, Wang H. Regular use of nephrotoxic medications is an independent risk factor for chronic kidney disease—results from a Chinese population study. Nephrology Dialysis Transplantation. 2011;26(6):1916-23.
  • 512. National Institute for Health and Clinical Excellence. NICE Clinical Guideline 38: Bipolar Disorder. 2006.
  • 513. Lipska KJ, Bailey CJ, Inzucchi SE. Use of Metformin in the Setting of Mild-toModerate Renal Insufficiency. Diabetes Care. 2011;34(6):1431-7.
  • 514. Rachmani R, Slavachevski I, Levi Z, Zadok B, Kedar Y, Ravid M. Metformin in patients with type 2 diabetes mellitus: reconsideration of traditional contraindications. European journal of internal medicine. 2002;13(7):428.
  • 515. Salpeter SR, Greyber E, Pasternak GA, Salpeter EE. Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. Cochrane Database of Systematic Reviews. 2010.
  • 516. Fellstrom BC, Jardine AG, Schmieder RE, Holdaas H, Bannister K, Beutler J, et al. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. The New England journal of medicine. 2009;360(14):1395-407.
  • 517. Ginsberg HN, Elam MB, Lovato LC, Crouse JR, 3rd, Leiter LA, Linz P, et al. Effects of combination lipid therapy in type 2 diabetes mellitus. The New England journal of medicine. 2010;362(17):1563-74.
  • 518. Januszkiewicz L. [The ACCORD Study Group. Effects of combination lipid therapy in type 2 diabetes mellitus]. Kardiologia polska. 2010;68(7):853-4; discussion 5.
  • 519. Keech A, Simes RJ, Barter P, Best J, Scott R, Taskinen MR, et al. Effects of longterm fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet. 2005;366(9500):1849-61.
  • 520. Wanner C, Krane V, Marz W, Olschewski M, Mann JF, Ruf G, et al. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. The New England journal of medicine. 2005;353(3):238-48.
  • 521. Limdi NA, Beasley TM, Baird MF, Goldstein JA, McGwin G, Arnett DK, et al. Kidney function influences warfarin responsiveness and hemorrhagic complications. J Am Soc Nephrol. 2009;20(4):912-21.
  • 522. Goldfarb S, McCullough PA, McDermott J, Gay SB. Contrast-induced acute kidney injury: specialty-specific protocols for interventional radiology, diagnostic computed tomography radiology, and interventional cardiology. Mayo Clinic proceedings. 2009;84(2):170-9.
  • 523. American College Radiology Guidelines. Manual on Contrast Media Version 8 [Available from: http://www.acr.org/B/media/ACR/Documents/PDF/QualitySafety/Resources/Contrast/Manual/ContrastNephrotoxicity.pdf. .
  • 524. European Society for Urological Radiology (ESUR). [Available from: http://www.esur.org/Contrast-media.51.0.html.
  • 525. Heinrich MC, Haberle L, Muller V, Bautz W, Uder M. Nephrotoxicity of iso-osmolar iodixanol compared with nonionic low-osmolar contrast media: meta-analysis of randomized controlled trials. Radiology. 2009;250(1):68-86.
  • 526. Perazella MA. Current Status of Gadolinium Toxicity in Patients with Kidney Disease. Clinical Journal of the American Society of Nephrology. 2009;4(2):461-9.
  • 527. Agarwal R, Brunelli SM, Williams K, Mitchell MD, Feldman HI, Umscheid CA. Gadolinium-based contrast agents and nephrogenic systemic fibrosis: a systematic review and meta-analysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2009;24(3):856-63.
  • 528. Saitoh T, Hayasaka K, Tanaka Y, Kuno T, Nagura Y. Dialyzability of gadodiamide in hemodialysis patients. Radiation medicine. 2006;24(6):445-51.
  • 529. Lien YH. Is bowel preparation before colonoscopy a risky business for the kidney? Nature clinical practice Nephrology. 2008;4(11):606-14.
  • 530. Markowitz GS, Perazella MA. Acute phosphate nephropathy. Kidney international. 2009;76(10):1027-34.
  • 531. Heher EC, Thier SO, Rennke H, Humphreys BD. Adverse renal and metabolic effects associated with oral sodium phosphate bowel preparation. Clinical journal of the American Society of Nephrology : CJASN. 2008;3(5):1494-503.
  • 532. Pálmadóttir VK, Gudmundsson H, Hardarson S, Árnadóttir M, Magnússon T, Andrésdóttir MB. Incidence and outcome of acute phosphate nephropathy in Iceland. PloS one. 2010 5(10):e13484.
  • 533. Wexner SD, Beck DE, Baron TH, Fanelli RD, Hyman N, Shen B, et al. A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). Gastrointestinal endoscopy. 2006;63(7):894-909.
  • 534. Brunelli SM. Association between oral sodium phosphate bowel preparations and kidney injury: a systematic review and meta-analysis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2009;53(3):448-56.
  • 535. Johanson JF, Popp JW, Jr., Cohen LB, Lottes SR, Forbes WP, Walker K, et al. A randomized, multicenter study comparing the safety and efficacy of sodium phosphate tablets with 2L polyethylene glycol solution plus bisacodyl tablets for colon cleansing. The American journal of gastroenterology. 2007;102(10):2238-46.
  • 536. Foley RN, Guo H, Snyder JJ, Gilbertson DT, Collins AJ. Septicemia in the United States dialysis population, 1991 to 1999. J Am Soc Nephrol. 2004;15(4):1038-45.
  • 537. Sarnak MJ, Jaber BL. Mortality caused by sepsis in patients with end-stage renal disease compared with the general population. Kidney international. 2000;58(4):1758-64.
  • 538. McIntyre P, Craig JC. Prevention of serious bacterial infection in children with nephrotic syndrome. Journal of paediatrics and child health. 1998;34(4):314-7.
  • 539. Vanholder R, Ringoir S. Infectious morbidity and defects of phagocytic function in end-stage renal disease: a review. J Am Soc Nephrol. 1993;3(9):1541-54.
  • 540. Hoen B, Paul-Dauphin A, Hestin D, Kessler M. EPIBACDIAL: a multicenter prospective study of risk factors for bacteremia in chronic hemodialysis patients. J Am Soc Nephrol. 1998;9(5):869-76.
  • 541. Ishani A, Collins AJ, Herzog CA, Foley RN. Septicemia, access and cardiovascular disease in dialysis patients: the USRDS Wave 2 study. Kidney international. 2005;68(1):311- 8.
  • 542. Fried LF, Katz R, Sarnak MJ, Shlipak MG, Chaves PH, Jenny NS, et al. Kidney function as a predictor of noncardiovascular mortality. J Am Soc Nephrol. 2005;16(12):3728- 35.
  • 543. Nissenson AR, Collins AJ, Hurley J, Petersen H, Pereira BJ, Steinberg EP. Opportunities for improving the care of patients with chronic renal insufficiency: current practice patterns. J Am Soc Nephrol. 2001;12(8):1713-20.
  • 544. US Renal Data System. Atlas of Chronic Kidney Disease in the United States. Bethesda. MD: National Institutes of Diabetes and Digestive and Kidney Diseases ed2007.
  • 545. Naqvi SB, Collins AJ. Infectious complications in chronic kidney disease. Advances in chronic kidney disease. 2006;13(3):199-204.
  • 546. US Renal Data System. Atlas of Chronic Kidney Disease in the United States. Bethesda2010. 547. Cohen G, Haag-Weber M, Horl WH. Immune dysfunction in uremia. Kidney international Supplement. 1997;62:S79-82.
  • 548. Minnaganti VR, Cunha BA. Infections associated with uremia and dialysis. Infectious disease clinics of North America. 2001;15(2):385-406, viii.
  • 549. Pesanti EL. Immunologic defects and vaccination in patients with chronic renal failure. Infectious disease clinics of North America. 2001;15(3):813-32.
  • 550. Kausz AT, Guo H, Pereira BJ, Collins AJ, Gilbertson DT. General medical care among patients with chronic kidney disease: opportunities for improving outcomes. J Am Soc Nephrol. 2005;16(10):3092-101.
  • 551. DaRoza G, Loewen A, Djurdjev O, Love J, Kempston C, Burnett S, et al. Stage of chronic kidney disease predicts seroconversion after hepatitis B immunization: earlier is better. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2003;42(6):1184-92.
  • 552. Kausz AT, Gilbertson DT. Overview of vaccination in chronic kidney disease. Advances in chronic kidney disease. 2006;13(3):209-14.
  • 553. McNulty CA, Bowen JK, Williams AJ. Hepatitis B vaccination in predialysis chronic renal failure patients a comparison of two vaccination schedules. Vaccine. 2005;23(32):4142-7.
  • 554. Gilbertson DT, Unruh M, McBean AM, Kausz AT, Snyder JJ, Collins AJ. Influenza vaccine delivery and effectiveness in end-stage renal disease. Kidney international. 2003;63(2):738-43.
  • 555. Dinits-Pensy M, Forrest GN, Cross AS, Hise MK. The use of vaccines in adult patients with renal disease. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005;46(6):997-1011.
  • 556. Nikoskelainen J, Koskela M, Forsstrom J, Kasanen A, Leinonen M. Persistence of antibodies to pneumococcal vaccine in patients with chronic renal failure. Kidney international. 1985;28(4):672-7.
  • 557. Miller ER, Alter MJ, Tokars JI. Protective effect of hepatitis B vaccine in chronic hemodialysis patients. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1999;33(2):356-60.
  • 558. Fattom A, Fuller S, Propst M, Winston S, Muenz L, He D, et al. Safety and immunogenicity of a booster dose of Staphylococcus aureus types 5 and 8 capsular polysaccharide conjugate vaccine (StaphVAX) in hemodialysis patients. Vaccine. 2004;23(5):656-63.
  • 559. Shinefield H, Black S, Fattom A, Horwith G, Rasgon S, Ordonez J, et al. Use of a Staphylococcus aureus conjugate vaccine in patients receiving hemodialysis. The New England journal of medicine. 2002;346(7):491-6.
  • 560. Parfrey PS, Griffiths SM, Barrett BJ, Paul MD, Genge M, Withers J, et al. Contrast material-induced renal failure in patients with diabetes mellitus, renal insufficiency, or both. A prospective controlled study. The New England journal of medicine. 1989;320(3):143-9.
  • 561. Chapin E, Zhan M, Hsu VD, Seliger SL, Walker LD, Fink JC. Adverse safety events in chronic kidney disease: the frequency of “multiple hits”. Clinical journal of the American Society of Nephrology : CJASN. 2010;5(1):95-101.
  • 562. Arora P, Kausz AT, Obrador GT, Ruthazer R, Khan S, Jenuleson CS, et al. Hospital utilization among chronic dialysis patients. J Am Soc Nephrol. 2000;11(4):740-6.
  • 563. Khan SS, Kazmi WH, Abichandani R, Tighiouart H, Pereira BJ, Kausz AT. Health care utilization among patients with chronic kidney disease. Kidney international. 2002;62(1):229-36.
  • 564. Becker BN, Coomer RW, Fotiadis C, Evanson J, Shyr Y, Hakim RM. Risk factors for hospitalization in well-dialyzed chronic hemodialysis patients. American journal of nephrology. 1999;19(5):565-70.
  • 565. Popovic JR, Kozak LJ. National hospital discharge survey: annual summary, 1998. Vital and health statistics Series 13, Data from the National Health Survey. 2000(148):1- 194.
  • 566. Thamer M, Ray NF, Fehrenbach SN, Richard C, Kimmel PL. Relative risk and economic consequences of inpatient care among patients with renal failure. J Am Soc Nephrol. 1996;7(5):751-62.
  • 567. Holland DC, Lam M. Predictors of hospitalization and death among pre-dialysis patients: a retrospective cohort study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2000;15(5):650-8.
  • 568. Culleton BF, Larson MG, Wilson PW, Evans JC, Parfrey PS, Levy D. Cardiovascular disease and mortality in a community-based cohort with mild renal insufficiency. Kidney international. 1999;56(6):2214-9.
  • 569. Meyer KB, Levey AS. Controlling the epidemic of cardiovascular disease in chronic renal disease: report from the National Kidney Foundation Task Force on cardiovascular disease. J Am Soc Nephrol. 1998;9(12 Suppl):S31-42.
  • 570. Drueke TB, Locatelli F, Clyne N, Eckardt KU, Macdougall IC, Tsakiris D, et al. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. The New England journal of medicine. 2006;355(20):2071-84.
  • 571. Singh AK, Szczech L, Tang KL, Barnhart H, Sapp S, Wolfson M, et al. Correction of anemia with epoetin alfa in chronic kidney disease. The New England journal of medicine. 2006;355(20):2085-98.
  • 572. De Coster C, McLaughlin K, Noseworthy TW. Criteria for referring patients with renal disease for nephrology consultation: a review of the literature. Journal of nephrology. 2010;23(4):399-407.
  • 573. Navaneethan SD, Nigwekar S, Sengodan M, Anand E, Kadam S, Jeevanantham V, et al. Referral to nephrologists for chronic kidney disease care: is non-diabetic kidney disease ignored? Nephron Clinical practice. 2007;106(3):c113-8.
  • 574. Navaneethan SD, Kandula P, Jeevanantham V, Nally JV, Jr., Liebman SE. Referral patterns of primary care physicians for chronic kidney disease in general population and geriatric patients. Clinical nephrology. 2010;73(4):260-7.
  • 575. Chan MR, Dall AT, Fletcher KE, Lu N, Trivedi H. Outcomes in patients with chronic kidney disease referred late to nephrologists: a meta-analysis. The American journal of medicine. 2007;120(12):1063-70.
  • 576. Smart NA, Titus TT. Outcomes of early versus late nephrology referral in chronic kidney disease: a systematic review. The American journal of medicine. 2011;124(11):1073- 80 e2.
  • 577. McLaughlin K, Manns B, Culleton B, Donaldson C, Taub K. An economic evaluation of early versus late referral of patients with progressive renal insufficiency. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2001;38(5):1122- 8.
  • 578. Epping-Jordan JE, Pruitt SD, Bengoa R, Wagner EH. Improving the quality of health care for chronic conditions. Quality & safety in health care. 2004;13(4):299-305.
  • 579. Korevaar J, Jansen M, Dekker F. When to initiate dialysis: effect of proposed US guidelines on survival. Lancet. 2001;358:1046-50.
  • 580. Traynor J, Simpson K, Geddes C, Deighan C, Fox J. Early initiation of dialysis fails to prolong survival in patients with end-stage renal failure. J Am Soc Nephrol. 2002;13(8):2125-32.
  • 581. Beddhu S, Samore MH, Roberts MS, Stoddard GJ, Ramkumar N, Pappas LM, et al. Impact of timing of initiation of dialysis on mortality. J Am Soc Nephrol. 2003;14(9):2305-12.
  • 582. Clark WF, Na Y, Rosansky SJ, Sontrop JM, Macnab JJ, Glassock RJ, et al. Association between estimated glomerular filtration rate at initiation of dialysis and mortality. CMAJ : Canadian Medical Association Journal. 2011;183(1):47-53.
  • 583. Hwang S-J, Yang W-C, Lin M-Y, Mau L-W, Chen H-C, Nephrology TSo. Impact of the clinical conditions at dialysis initiation on mortality in incident haemodialysis patients: a national cohort study in Taiwan. Nephrology Dialysis Transplantation. 2010;25(8):2616-24.
  • 584. Kazmi WH, Gilbertson DT, Obrador GT, Guo H, Pereira BJ, Collins AJ, et al. Effect of comorbidity on the increased mortality associated with early initiation of dialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005;46(5):887-96.
  • 585. Lassalle M, Labeeuw M, Frimat L, Villar E, Joyeux V, Couchoud C, et al. Age and comorbidity may explain the paradoxical association of an early dialysis start with poor survival. Kidney international. 2010;77(8):700-7.
  • 586. Shiao CC, Huang JW, Chien KL, Chuang HF, Chen YM, Wu KD. Early initiation of dialysis and late implantation of catheters adversely affect outcomes of patients on chronic peritoneal dialysis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2008;28(1):73-81.
  • 587. Stel VS, Dekker Fw Fau – Ansell D, Ansell D Fau – Augustijn H, Augustijn H Fau – Casino FG, Casino Fg Fau – Collart F, Collart F Fau – Finne P, et al. Residual renal function at the start of dialysis and clinical outcomes. (1460-2385 (Electronic)).
  • 588. Tang SC, Ho YW, Tang AW, Cheng YY, Chiu FH, Lo WK, et al. Delaying initiation of dialysis till symptomatic uraemia–is it too late? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2007;22(7):1926-32.
  • 589. Wright S, Klausner D, Baird B, Williams ME, Steinman T, Tang H, et al. Timing of dialysis initiation and survival in ESRD. Clinical journal of the American Society of Nephrology : CJASN. 2010;5(10):1828-35.
  • 590. Wilson B, Harwood L, Locking-Cusolito H, Chen SJ, Heidenheim P, Craik D, et al. Optimal timing of initiation of chronic hemodialysis? Hemodialysis international International Symposium on Home Hemodialysis. 2007;11(2):263-9.
  • 591. Sawhney S, Djurdjev O, Simpson K, Macleod A, Levin A. Survival and dialysis initiation: comparing British Columbia and Scotland registries. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2009;24(10):3186-92.
  • 592. Cooper BA, Branley P, Bulfone L, Collins JF, Craig JC, Fraenkel MB, et al. A randomized, controlled trial of early versus late initiation of dialysis. The New England journal of medicine. 2010;363(7):609-19.
  • 593. Rosansky SJ, Eggers P, Jackson K, Glassock R, Clark WF. Early start of hemodialysis may be harmful. Archives of internal medicine. 2011;171(5):396-403.
  • 594. Harris A, Cooper BA, Li JJ, Bulfone L, Branley P, Collins JF, et al. Cost-effectiveness of initiating dialysis early: a randomized controlled trial. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2011;57(5):707-15.
  • 595. Davison SN. Pain in hemodialysis patients: prevalence, cause, severity, and management. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2003;42(6):1239-47.
  • 596. Davison SN, Jhangri GS, Johnson JA. Cross-sectional validity of a modified Edmonton symptom assessment system in dialysis patients: a simple assessment of symptom burden. Kidney international. 2006;69(9):1621-5.
  • 597. Davison SN, Jhangri GS, Johnson JA. Longitudinal validation of a modified Edmonton symptom assessment system (ESAS) in haemodialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2006;21(11):3189-95.
  • 598. Murphy EL, Murtagh FE, Carey I, Sheerin NS. Understanding symptoms in patients with advanced chronic kidney disease managed without dialysis: use of a short patientcompleted assessment tool. Nephron Clinical practice. 2009;111(1):c74-80.
  • 599. Murtagh FE, Addington-Hall JM, Donohoe P, Higginson IJ. Symptom management in patients with established renal failure managed without dialysis. EDTNA/ERCA journal. 2006;32(2):93-8.
  • 600. Murtagh FE, Addington-Hall JM, Edmonds PM, Donohoe P, Carey I, Jenkins K, et al. Symptoms in advanced renal disease: a cross-sectional survey of symptom prevalence in stage 5 chronic kidney disease managed without dialysis. Journal of palliative medicine. 2007;10(6):1266-76.
  • 601. Saini T, Murtagh FE, Dupont PJ, McKinnon PM, Hatfield P, Saunders Y. Comparative pilot study of symptoms and quality of life in cancer patients and patients with end stage renal disease. Palliative medicine. 2006;20(6):631-6.
  • 602. Temel JS, Greer JA, Muzikansky A, Gallagher ER, Admane S, Jackson VA, et al. Early palliative care for patients with metastatic non-small-cell lung cancer. The New England journal of medicine. 2010;363(8):733-42.
  • 603. Chandna SM, Da Silva-Gane M, Marshall C, Warwicker P, Greenwood RN, Farrington K. Survival of elderly patients with stage 5 CKD: comparison of conservative management and renal replacement therapy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2011;26(5):1608-14.
  • 604. Davison SN. End-of-life care preferences and needs: perceptions of patients with chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN. 2010;5(2):195-204.
  • 605. Davidson SN, Murtagh FE, Higginson IJ. Methodological considerations for end-oflife research in patients with chronic kidney disease. Journal of nephrology. 2008;21(3):268- 82.
  • 606. De Biase V, Tobaldini O, Boaretti C, Abaterusso C, Pertica N, Loschiavo C, et al. Prolonged conservative treatment for frail elderly patients with end-stage renal disease: the Verona experience. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2008;23(4):1313-7.
  • 607. Ellam T, El-Kossi M, Prasanth KC, El-Nahas M, Khwaja A. Conservatively managed patients with stage 5 chronic kidney disease–outcomes from a single center experience. QJM : monthly journal of the Association of Physicians. 2009;102(8):547-54.
  • 608. Germain MJ, Kurella Tamura M, Davison SN. Palliative care in CKD: the earlier the better. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2011;57(3):378-80.
  • 609. Murray A, Arko C, Chen S. Use of hospice in the United States dialysis population. Clinical journal of the American Society of Nephrology : CJASN. 2006;1:1248–55.
  • 610. Hearn J, Higginson I. Do specialist palliative care teams improve outcomes for cancer patients? A systematic literature review. . Palliative medicine. 1998;12:317–32.
  • 611. Higginson IJ, Wade AM, McCarthy M. Effectiveness of two palliative support teams. Journal of public health medicine. 1992;14(1):50-6.
  • 612. Ventafridda V, De Conno F, Vigano A, Ripamonti C, Gallucci M, Gamba A. Comparison of home and hospital care of advanced cancer patients. Tumori. 1989;75(6):619-25.
  • 613. Wallston KA, Burger C, Smith RA, Baugher RJ. Comparing the quality of death for hospice and non-hospice cancer patients. Medical care. 1988;26(2):177-82.
  • 614. Fassbender K, Smythe J, Carson M. Report of the Institute for Public Economics Health Research Group to Alberta Health and Wellness: cost and utilization of health care services at end of life in Alberta, 1999–2002. . Edmonton, AB: University of Alberta; 2006.
  • 615. Higgins JPT, Green S, Cochrane Collaboration. Cochrane handbook for systematic reviews of interventions. Chichester, England ; Hoboken, NJ: Wiley-Blackwell; 2008. xxi, 649 p. p. 616. Beilby JJ, Silagy CA. Trials of providing costing information to general practitioners: a systematic review. The Medical journal of Australia. 1997;167(2):89-92.
  • 617. Davis DA, Thomson MA, Oxman AD, Haynes RB. Changing physician performance. A systematic review of the effect of continuing medical education strategies. JAMA. 1995;274(9):700-5.
  • 618. Grimshaw JM, Thomas RE, MacLennan G, Fraser C, Ramsay CR, Vale L, et al. Effectiveness and efficiency of guideline dissemination and implementation strategies. Health technology assessment (Winchester, England). 2004;8(6):iii-iv, 1-72.
  • 619. Hunt DL, Haynes RB, Hanna SE, Smith K. Effects of computer-based clinical decision support systems on physician performance and patient outcomes: a systematic review. JAMA. 1998;280(15):1339-46.
  • 620. Jamtvedt G, Young JM, Kristoffersen DT, O’Brien MA, Oxman AD. Audit and feedback: effects on professional practice and health care outcomes. The Cochrane database of systematic reviews. 2006(2):CD000259.
  • 621. Oxman AD, Thomson MA, Davis DA, Haynes RB. No magic bullets: a systematic review of 102 trials of interventions to improve professional practice. CMAJ : Canadian Medical Association journal = journal de l’Association medicale canadienne. 1995;153(10):1423-31.
  • 622. Smith WR. Evidence for the effectiveness of techniques To change physician behavior. Chest. 2000;118(2 Suppl):8S-17S.
  • 623. Sullivan F, Mitchell E. Has general practitioner computing made a difference to patient care? A systematic review of published reports. Bmj. 1995;311(7009):848-52.
  • 624. Donabedian A. The quality of care. How can it be assessed? 1988. Archives of pathology & laboratory medicine. 1997;121(11):1145-50.
  • 625. Donabedian A. Evaluating the quality of medical care. 1966. The Milbank quarterly. 2005;83(4):691-729.
  • 626. Secretaría de salud. Tratamiento Sustitutivo de la función renal. Diálisis y Hemodiálisis en la insuficiencia renal crónica. Segundo y tercer nivel de atención. México: Centro Nacional de Excelencia Tecnológica en salud (CENETEC); 2014. 59 p.
  • 627. Ministry of Health Malaysia. Management of chronic kindney disease in adults. Malasia2011. 58 p.
  • 628. Govern de les Illes Balears. Guía para el tratamiento conservador en pacientes con enfermedad renal crónica avanzada (ERCA) [Internet] Islas Baleares: [Publisher unknown]; 2015 [Available from: http://www.caib.es/sacmicrofront/archivopub.do?ctrl=MCRST3145ZI190069&id=190069.
  • 629. Ministry of Health. Managing of chronic kidney disease in primary care: national consensus statement. Wellington, New Zealand: Ministry of Health; 2015.
  • 630. Nesrallah GE, Mustafa RA, Clark WF, Bass A, Barnieh L, Hemmelgarn BR, et al. Canadian Society of Nephrology 2014 clinical practice guideline for timing the initiation of chronic dialysis. CMAJ : Canadian Medical Association journal = journal de l’Association medicale canadienne. 2014;186(2):112-7.
  • 631. National Clinical Guideline Centre. Anaemia management in chronic kidney disease. Partial update 2015. Clinical Guideline Methods, evidence and recommendations. London: National Institute for Clinical Excellence (NICE); The Royal College of Physicians; 2015.
  • 632. National Institute for Clinical Excellence. Hyperphosphataemia in chronic kidney disease. Management of hyperphosphataemia in patients with stage 4 or 5 chronic kidney disease. NICE clinical guideline 157. Manchester: National Institute for Health and Care Excellence (NICE); 2013.
  • 633. Rocco MV, Soucie JM, Reboussin DM, McClellan WM. Risk factors for hospital utilization in chronic dialysis patients. Southeastern Kidney Council (Network 6). J Am Soc Nephrol. 1996;7(6):889-96.
  • 634. Programa de salud renal Uruguay. Guías de práctica clínica en el diagnóstico y tratamiento de la enfermedad renal crónica. Montevideo (UY)2013. 65 p.
  • 635. Bose B, Badve SV, Hiremath SS, Boudville N, Brown FG, Cass A, et al. Effects of uric acid-lowering therapy on renal outcomes: a systematic review and meta-analysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association – European Renal Association. 2014;29(2):406-13.
Anterior Siguiente

CLIC AQUÍ Y DÉJANOS TU COMENTARIO

Deja un comentario

Tu dirección de correo electrónico no será publicada. Los campos obligatorios están marcados con *